At physiologic albumin/oleate concentrations oleate uptake by isolated hepatocytes, cardiac myocytes, and adipocytes is a saturable function of the unbound oleate concentration. Uptake kinetics are consistent with the conventional theory.
about
Spexin is a novel human peptide that reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents with diet-induced obesityFacilitated diffusion and membrane permeation of fatty acid in albumin solutions.3T3 fibroblasts transfected with a cDNA for mitochondrial aspartate aminotransferase express plasma membrane fatty acid-binding protein and saturable fatty acid uptakeVLDL hydrolysis by LPL activates PPAR-alpha through generation of unbound fatty acids.Regulatable fatty acid transport mechanisms are central to the pathophysiology of obesity, fatty liver, and metabolic syndrome.Adipocyte accumulation of long-chain fatty acids in obesity is multifactorial, resulting from increased fatty acid uptake and decreased activity of genes involved in fat utilization.Insulin- and leptin-regulated fatty acid uptake plays a key causal role in hepatic steatosis in mice with intact leptin signaling but not in ob/ob or db/db mice.Fatty acid (FFA) transport in cardiomyocytes revealed by imaging unbound FFA is mediated by an FFA pump modulated by the CD36 protein.New insights into long-chain fatty acid uptake by heart muscle: a crucial role for fatty acid translocase/CD36Cardiomyocyte triglyceride accumulation and reduced ventricular function in mice with obesity reflect increased long chain Fatty Acid uptake and de novo Fatty Acid synthesis.Effect of fatty acids on human bone marrow mesenchymal stem cell energy metabolism and survival.Effect of diet on human adipose tissue metabolism.A novel mouse model of lipotoxic cardiomyopathy.Facilitated long chain fatty acid uptake by adipocytes remains upregulated relative to BMI for more than a year after major bariatric surgical weight loss.Regulated membrane transport of free fatty acids in adipocytes: role in obesity and non-insulin dependent diabetes mellitus.Is there facilitated uptake of fatty acids by the liver? Interpretation and analysis of experimental data.Chronic ethanol consumption increases cardiomyocyte fatty acid uptake and decreases ventricular contractile function in C57BL/6J miceFatty acid-specific fluorescent probes and their use in resolving mixtures of unbound free fatty acids in equilibrium with albuminSelective up-regulation of fatty acid uptake by adipocytes characterizes both genetic and diet-induced obesity in rodents.An understanding of flow- and diffusion-limited vs. carrier-mediated hepatic transport: a simulation study.Mathematical Models Suggest Facilitated Fatty Acids Crossing of the Luminal Membrane in the Cardiac Muscle.Zonation of hepatic fat accumulation: insights from mathematical modelling of nutrient gradients and fatty acid uptake.Training-induced elevation in FABP(PM) is associated with increased palmitate use in contracting muscle.Saturation kinetics of palmitate uptake in perfused skeletal muscle.Testing and characterizing enzymes and membrane-bound carrier proteins acting on amphipathic ligands in the presence of bilayer membrane material and soluble binding protein. Application to the uptake of oleate into isolated cellsA direct role for serum albumin in the cellular uptake of long-chain fatty acidsPalmitate uptake by neonatal rat myocytes and hepatocytes. Role of extracellular protein.Common mechanisms of monoacylglycerol and fatty acid uptake by human intestinal Caco-2 cells.Electrostimulation enhances FAT/CD36-mediated long-chain fatty acid uptake by isolated rat cardiac myocytes.Cell culture models of fatty acid overload: Problems and solutions.Differences in adipocyte long chain fatty acid uptake in Osborne-Mendel and S5B/Pl rats in response to high-fat diets.Effect of an unstirred layer on the membrane permeability of anandamide.A grass-based diet favours muscle n-3 long-chain PUFA deposition without modifying gene expression of proteins involved in their synthesis or uptake in Charolais steers.Blood-brain barrier transport and protein binding of flumazenil and iomazenil in the rat: implications for neuroreceptor studies.Long-chain fatty acid uptake is upregulated in omental adipocytes from patients undergoing bariatric surgery for obesity.Endothelin-1 decreases CD36 protein expression in vascular smooth muscle cells.
P2860
Q24337677-47B850C8-BC63-47E5-817E-593A2CEB6FA9Q33858128-92BFD9F2-0813-4774-9BD3-6F985C82F409Q33875742-8F8B77B2-C42D-45B0-B408-49E0BAC81D60Q33993114-B9176C21-99B9-4B7B-9E7A-6589ECBB6139Q34207748-91974D31-AEB3-4587-A0B7-43AA70F9DFC0Q34207754-19E081AF-A714-4BAC-ABAB-4A0CF8D9E0E4Q34212126-72B5CD5B-51F5-41FD-AFCC-F91142FDE0BCQ34575762-1AD6EAEA-47DE-4E28-BE30-8263369C1F4EQ34712392-90C0F60C-D5CB-416E-82CE-A8558F80C4C1Q35550651-8B517639-500C-40F7-98AF-947608B400C7Q35576599-D00C75F3-EE66-463B-9214-3150147EA48CQ35655792-C29623AD-3B85-4EFC-914E-4B6A498AB272Q36016938-B878EFB3-BE96-49C6-A985-5FC1E7609A50Q36425655-09B3FEC4-7A4A-4C9A-9A3F-035954C74AEAQ36647308-D718E9D1-B08C-4DAE-84DC-B4CDB9F7B033Q36694206-E48B124F-F6F9-4760-9F6C-7CDD0236F88AQ36824118-B383E071-D628-4081-8830-340FBDF90259Q36844298-E59036DD-8250-471F-A4F7-AFF49288DE15Q38320251-E58818DB-7C42-4BAD-9177-6C7CC2E763CFQ38462832-7011B947-0791-4BE7-9619-4573997254B3Q39134491-0775DB02-5C40-4A77-A858-6E8DD7C6FE1CQ40081986-E0E0FAD3-B780-405A-9EB9-EE2B5C2324E1Q41679753-D3B09E8A-2633-4E40-9E00-350C97590643Q41827600-CEEB62CC-DCFE-4F2E-8B69-96BB2310C764Q41932511-6845B895-7B25-41C2-8640-092ED44D30C3Q42107847-6A9F87FA-3946-431E-BF35-DFEDD750DF02Q43628308-8CD77D11-DCCB-470A-9A13-820AE7672819Q43730242-DA735517-64F9-4C8D-A1D1-76C5AE8376B5Q43733886-37A9C8E9-8B0D-477A-9AED-734739CE9779Q46258336-7832B5FC-BCEA-4514-B7F2-922E02803329Q46807089-BB3AC548-80E5-4B8D-9650-08501A865E1EQ46859636-AB23445B-F9DB-46E8-87BF-F7B6DE790B46Q47857855-E2355825-FC9C-4314-A902-091CB1396E3BQ48118275-D70E1658-2F8A-4587-99D7-2BF6AD255703Q51525495-FAF8D414-650D-4439-A0D7-6C46D40DD04BQ53598260-7DB0D008-719A-4543-B510-1DFA418373CA
P2860
At physiologic albumin/oleate concentrations oleate uptake by isolated hepatocytes, cardiac myocytes, and adipocytes is a saturable function of the unbound oleate concentration. Uptake kinetics are consistent with the conventional theory.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
At physiologic albumin/oleate ...... with the conventional theory.
@ast
At physiologic albumin/oleate ...... with the conventional theory.
@en
type
label
At physiologic albumin/oleate ...... with the conventional theory.
@ast
At physiologic albumin/oleate ...... with the conventional theory.
@en
prefLabel
At physiologic albumin/oleate ...... with the conventional theory.
@ast
At physiologic albumin/oleate ...... with the conventional theory.
@en
P2093
P2860
P356
P1476
At physiologic albumin/oleate ...... with the conventional theory.
@en
P2093
D Sorrentino
R B Robinson
P2860
P304
P356
10.1172/JCI114301
P407
P577
1989-10-01T00:00:00Z