Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome.
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Li-fraumeni syndromeSmall-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapyAtm heterozygous deficiency enhances development of mammary carcinomas in p53 heterozygous knockout mice.Are Trp53 rescue of Brca1 embryonic lethality and Trp53/Brca1 breast cancer association related?Knockout and transgenic mice of Trp53: what have we learned about p53 in breast cancer?JNK signalling in cancer: in need of new, smarter therapeutic targetsGenetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer riskOvca1 regulates cell proliferation, embryonic development, and tumorigenesisASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63p53 haploinsufficiency profoundly accelerates the onset of tongue tumors in mice lacking the xeroderma pigmentosum group A gene.Mouse models of human familial cancer syndromes.Influence of Hoxa5 on p53 tumorigenic outcome in mice.Role of JNK in a Trp53-dependent mouse model of breast cancer.Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice.Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.Stress signaling and the shaping of the mammary tissue in development and cancer.Map making in the 21st century: charting breast cancer susceptibility pathways in rodent models.p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesisMitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressiveIn vivo analysis of p53 tumor suppressor function using genetically engineered mouse modelsDevelopment and translational imaging of a TP53 porcine tumorigenesis modelIGF1 activates cell cycle arrest following irradiation by reducing binding of ΔNp63 to the p21 promoterMurine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient miceOf mice and women: A short history of mouse mammary cancer research with an emphasis on the paradigms inspired by the transplantation method.Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency.Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivoThe Trp53 hemizygous mouse in pharmaceutical development: points to consider for pathologists.siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors.Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomasp53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome.Mouse models with modified p53 sequences to study cancer and ageing.Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer.Genetically engineered mice as experimental tools to dissect the critical events in breast cancerTransgenic and knockout mice models to reveal the functions of tumor suppressor genes.Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment.The melanocyte differentiation program predisposes to metastasis after neoplastic transformation.Choosing a mouse model: experimental biology in context--the utility and limitations of mouse models of breast cancer.Differential mammary gland development in FVB and C57Bl/6 mice: implications for breast cancer research.Replacement of E-cadherin by N-cadherin in the mammary gland leads to fibrocystic changes and tumor formation.Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells.
P2860
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P2860
Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Development of spontaneous mam ...... odel for Li-Fraumeni syndrome.
@ast
Development of spontaneous mam ...... odel for Li-Fraumeni syndrome.
@en
type
label
Development of spontaneous mam ...... odel for Li-Fraumeni syndrome.
@ast
Development of spontaneous mam ...... odel for Li-Fraumeni syndrome.
@en
prefLabel
Development of spontaneous mam ...... odel for Li-Fraumeni syndrome.
@ast
Development of spontaneous mam ...... odel for Li-Fraumeni syndrome.
@en
P2093
P2860
P1476
Development of spontaneous mam ...... odel for Li-Fraumeni syndrome.
@en
P2093
C Kuperwasser
E S Dickinson
F S Kittrell
G D Hurlbut
R Laucirica
P2860
P304
P356
10.1016/S0002-9440(10)64853-5
P407
P577
2000-12-01T00:00:00Z