Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis. - Wikidata - wikimedia - TriplyDB

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.

http://www.wikidata.org/entity/Q35834606

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The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis A quarter century of granzymes MHC class I expression protects rat colon carcinoma cells from hepatic natural killer cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway Regulatory T Cells: Molecular Actions on Effector Cells in Immune Regulation Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B Granzyme B enters the mitochondria in a Sam50-, Tim22- and mtHsp70-dependent manner to induce apoptosis.Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis.DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity Hydroxyl radical-induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation.Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.Apoptosis and liver diseases: recent concepts of mechanism and significance.Advances in the non-surgical treatment of melanoma.Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells.Death by a thousand cuts: granzyme pathways of programmed cell death Perforin: more than just a pore-forming protein.Targeted apoptosis activation with GrB/scFvMEL modulates melanoma growth, metastatic spread, chemosensitivity, and radiosensitivity.Inhibition of interleukin-1beta-stimulated dedifferentiation of chondrocytes via controlled release of CrmA from hyaluronic acid-chitosan microspheres Granzyme B-induced mitochondrial ROS are required for apoptosis Liver immunobiology.Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis.Pseudomonas aeruginosa ExoT Induces Mitochondrial Apoptosis in Target Host Cells in a Manner That Depends on Its GTPase-activating Protein (GAP) Domain Activity.Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis.Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity.miR-143 or miR-145 overexpression increases cetuximab-mediated antibody-dependent cellular cytotoxicity in human colon cancer cells.Mechanisms of granule-dependent killing.Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure A novel p38 mitogen-activated protein kinase/Elk-1 transcription factor-dependent molecular mechanism underlying abnormal endothelial cell proliferation in plexogenic pulmonary arterial hypertension Acid-sensing ion channel 1a regulates the survival of nucleus pulposus cells in the acidic environment of degenerated intervertebral discs.Immune-mediated liver diseases: programmed cell death ligands and circulating apoptotic markers.Perforin and Fas act together in the induction of apoptosis, and both are critical in the clearance of lymphocytic choriomeningitis virus infection.Orphan granzymes find a home.Cell death-independent functions of granzymes: hit viruses where it hurts.Controversies in granzyme biology.Staying alive: cell death in antiviral immunity.Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway.ZIP1 and zinc inhibits fluoride-induced apoptosis in MC3T3-E1 cells.Effect of ziram on natural killer, lymphokine-activated killer, and cytotoxic T lymphocyte activity.

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P2860

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.

http://www.wikidata.org/entity/Q35834606

description

1999 nî lūn-bûn

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1999年论文

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name

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.

@ast

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.

@en

type

label

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.

@ast

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.

@en

prefLabel

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.

@ast

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.

@en

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Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis.

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Greenberg AH

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Lieberman J

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MacDonald G

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Shi L

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Vande Velde C

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P2860

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

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