Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre.
about
The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary ciliumSpata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retinaUsher syndrome: animal models, retinal function of Usher proteins, and prospects for gene therapyThe homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment developmentDifferent roles for KIF17 and kinesin II in photoreceptor development and maintenance.Trafficking in and to the primary cilium.Gene therapy prevents photoreceptor death and preserves retinal function in a Bardet-Biedl syndrome mouse model.Spatial distribution of intraflagellar transport proteins in vertebrate photoreceptorsDistinct functions for IFT140 and IFT20 in opsin transportIFT20 is required for opsin trafficking and photoreceptor outer segment developmentmyosin 7aa(-/-) mutant zebrafish show mild photoreceptor degeneration and reduced electroretinographic responses.Diverse cell type-specific mechanisms localize G protein-coupled receptors to Caenorhabditis elegans sensory ciliaDysfunction of heterotrimeric kinesin-2 in rod photoreceptor cells and the role of opsin mislocalization in rapid cell death.Generation of Cre transgenic mice with postnatal RPE-specific ocular expressionHeterotrimeric kinesin-2 (KIF3) mediates transition zone and axoneme formation of mouse photoreceptorsSupporting conditional mouse mutagenesis with a comprehensive cre characterization resource.Photoreceptor sensory cilia and ciliopathies: focus on CEP290, RPGR and their interacting proteins.Beyond knockouts: cre resources for conditional mutagenesis.Unexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins.Protein sorting, targeting and trafficking in photoreceptor cellsIntraflagellar transport and the sensory outer segment of vertebrate photoreceptors.The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptorsDepleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or functionThe molecular architecture of ribbon presynaptic terminalsInducible expression of cre recombinase in the retinal pigmented epithelium.Trafficking of membrane proteins to cone but not rod outer segments is dependent on heterotrimeric kinesin-II.R9AP overexpression alters phototransduction kinetics in iCre75 mice.Conditional gene targeting: dissecting the cellular mechanisms of retinal degenerations.Kinesin-2 motors transport IFT-particles, dyneins and tubulin subunits to the tips of Caenorhabditis elegans sensory cilia: relevance to vision research?Efficient induction of productive Cre-mediated recombination in retinal pigment epithelium.Molecular basis for photoreceptor outer segment architecture.Photoreceptor IFT complexes containing chaperones, guanylyl cyclase 1 and rhodopsin.Photoreceptor outer segment as a sink for membrane proteins: hypothesis and implications in retinal ciliopathies.Ciliary transport of opsin.Characterization of transgenic mouse lines expressing Cre recombinase in the retina.Expression of Cre recombinase in retinal Müller cells.Live-cell imaging evidence for the ciliary transport of rod photoreceptor opsin by heterotrimeric kinesin-2.The cytoplasmic tail of rhodopsin triggers rapid rod degeneration in kinesin-2 mutants.Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish.Arl3 and RP2 regulate the trafficking of ciliary tip kinesins.
P2860
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P2860
Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Analysis of kinesin-2 function ...... nockout of Kif3a with RHO-Cre.
@ast
Analysis of kinesin-2 function ...... nockout of Kif3a with RHO-Cre.
@en
type
label
Analysis of kinesin-2 function ...... nockout of Kif3a with RHO-Cre.
@ast
Analysis of kinesin-2 function ...... nockout of Kif3a with RHO-Cre.
@en
prefLabel
Analysis of kinesin-2 function ...... nockout of Kif3a with RHO-Cre.
@ast
Analysis of kinesin-2 function ...... nockout of Kif3a with RHO-Cre.
@en
P2093
P2860
P50
P356
P1476
Analysis of kinesin-2 function ...... knockout of Kif3a with RHO-Cre
@en
P2093
David S Williams
Karen Teofilo
Lawrence S B Goldstein
Leonard Feiner
P2860
P304
P356
10.1167/IOVS.06-0032
P407
P577
2006-11-01T00:00:00Z