High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection.
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Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1Characterization of three nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. Australian Long-Term Nonprogressor Study Group.Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulationImmunity to retroviral infection: the Friend virus modelThe accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner.HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, HckThe pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaquesRefined solution structure and backbone dynamics of HIV-1 Nef.Human immunodeficiency virus vaccine trialsGoing wild: lessons from naturally occurring T-lymphotropic lentivirusesChemical library screens targeting an HIV-1 accessory factor/host cell kinase complex identify novel antiretroviral compoundsDevelopment and validation of a high-content bimolecular fluorescence complementation assay for small-molecule inhibitors of HIV-1 Nef dimerization.Replicative capacity of human immunodeficiency virus type 1 transmitted from mother to child is associated with pediatric disease progression rateCCR2-64I polymorphism is not associated with altered CCR5 expression or coreceptor function.Meta-analysis to test the association of HIV-1 nef amino acid differences and deletions with disease progressionPathogenic conversion of live attenuated simian immunodeficiency virus vaccines is associated with expression of truncated NefJembrana disease virus Tat can regulate human immunodeficiency virus (HIV) long terminal repeat-directed gene expression and can substitute for HIV Tat in viral replication.Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulationUnusual polymorphisms in human immunodeficiency virus type 1 associated with nonprogressive infection.Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of disease.In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail.Construction and in vitro properties of a series of attenuated simian immunodeficiency viruses with all accessory genes deleted.Nef enhances human immunodeficiency virus type 1 infectivity resulting from intervirion fusion: evidence supporting a role for Nef at the virion envelope.CD4 down-modulation by human immunodeficiency virus type 1 Nef correlates with the efficiency of viral replication and with CD4(+) T-cell depletion in human lymphoid tissue ex vivoSeparation of human immunodeficiency virus type 1 replication from nef-mediated pathogenesis in the human thymusSimian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression.Association of single nucleotide polymorphisms in the lens epithelium-derived growth factor (LEDGF/p75) with HIV-1 infection outcomes in Brazilian HIV-1+ individualsPathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo.Positive and negative aspects of the human immunodeficiency virus protease: development of inhibitors versus its role in AIDS pathogenesisHigh viral fitness during acute HIV-1 infection.Nef stimulates human immunodeficiency virus type 1 replication in primary T cells by enhancing virion-associated gp120 levels: coreceptor-dependent requirement for Nef in viral replication.Interaction of HIV-1 Nef protein with the host protein Alix promotes lysosomal targeting of CD4 receptor.Longitudinal analysis of human immunodeficiency virus type 1 nef/long terminal repeat sequences in a cohort of long-term survivors infected from a single source.Inefficient enhancement of viral infectivity and CD4 downregulation by human immunodeficiency virus type 1 Nef from Japanese long-term nonprogressorsCoreceptor phenotype of natural human immunodeficiency virus with nef deleted evolves in vivo, leading to increased virulence.Nef neutralizes the ability of exosomes from CD4+ T cells to act as decoys during HIV-1 infection.Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressorDendritic cell-mediated HIV-1 infection of T cells demonstrates a direct relationship to plasma viral RNA levelsNef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes.
P2860
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P2860
High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
High frequency of defective ne ...... ciency virus type 1 infection.
@ast
High frequency of defective ne ...... ciency virus type 1 infection.
@en
type
label
High frequency of defective ne ...... ciency virus type 1 infection.
@ast
High frequency of defective ne ...... ciency virus type 1 infection.
@en
prefLabel
High frequency of defective ne ...... ciency virus type 1 infection.
@ast
High frequency of defective ne ...... ciency virus type 1 infection.
@en
P2093
P2860
P1433
P1476
High frequency of defective ne ...... iciency virus type 1 infection
@en
P2093
F Kirchhoff
J L Sullivan
J Skowronski
R C Desrosiers
T C Greenough
P2860
P304
P407
P577
1996-11-01T00:00:00Z