Application of a cocktail approach to screen cytochrome P450 BM3 libraries for metabolic activity and diversity.

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Steroids hydroxylation catalyzed by the monooxygenase mutant 139-3 from Bacillus megaterium BM3.Alleviation of pain in painful diabetic neuropathy.Laboratory-Scale Hydroxylation of Steroids by P450BM3 Variants.

P2860

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P2860

Application of a cocktail approach to screen cytochrome P450 BM3 libraries for metabolic activity and diversity.

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http://www.wikidata.org/entity/Q35890993

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

Application of a cocktail appr ...... abolic activity and diversity.

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Application of a cocktail appr ...... abolic activity and diversity.

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Application of a cocktail appr ...... abolic activity and diversity.

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Application of a cocktail appr ...... abolic activity and diversity.

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Application of a cocktail appr ...... abolic activity and diversity.

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Application of a cocktail appr ...... abolic activity and diversity.

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P1476

Application of a cocktail appr ...... tabolic activity and diversity

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P2093

Cornelis Tump

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Geert Postma

http://www.w3.org/2001/XMLSchema#string

Jan N M Commandeur

http://www.w3.org/2001/XMLSchema#string

Jelle Reinen

http://www.w3.org/2001/XMLSchema#string

Maarten Honing

http://www.w3.org/2001/XMLSchema#string

Tom Bloemberg

http://www.w3.org/2001/XMLSchema#string

P2860

Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES

Data processing for mass spectrometry-based metabolomics.

Cytochrome p450 and chemical toxicology.

Development of an in vitro drug-drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds.

Application of a fluorescence-based continuous-flow bioassay to screen for diversity of cytochrome P450 BM3 mutant libraries.

Efficient screening of cytochrome P450 BM3 mutants for their metabolic activity and diversity toward a wide set of drug-like molecules in chemical space.

Role of residue 87 in the activity and regioselectivity of clozapine metabolism by drug-metabolizing CYP102A1 M11H: application for structural characterization of clozapine GSH conjugates.

Active site substitution A82W improves the regioselectivity of steroid hydroxylation by cytochrome P450 BM3 mutants as rationalized by spin relaxation nuclear magnetic resonance studies.

A single active site mutation inverts stereoselectivity of 16-hydroxylation of testosterone catalyzed by engineered cytochrome P450 BM3.

P2888

s00216-015-9241-x

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1425-1443

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scholarly article

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10.1007/S00216-015-9241-X

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English

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408

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Jasper Engel

Nico P Vermeulen

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2016-01-11T00:00:00Z

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290219466

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26753974

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4723632

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Application of a cocktail approach to screen cytochrome P450 BM3 libraries for metabolic activity and diversity.

about

P2860

P2860

Application of a cocktail approach to screen cytochrome P450 BM3 libraries for metabolic activity and diversity.

description

name

type

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P1433

P1476

P2093

P2860

P2888

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P31

P356

P407

P433

P478

P50

P577

P5875

P698

P932

P356

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P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

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P50

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P5875

P698

P932