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Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cellsThe Axin1 scaffold protein promotes formation of a degradation complex for c-MycInhibition of c-Myc activity by ribosomal protein L11O-GlcNAcylation and Metabolic Reprograming in CancerPre-Anchoring of Pin1 to Unphosphorylated c-Myc in a Fuzzy Complex Regulates c-Myc Activity.Metabolic maintenance of cell asymmetry following division in activated T lymphocytesStructural Basis for High-Affinity Peptide Inhibition of Human Pin1Epigallocatechin-gallate Suppresses Tumorigenesis by Directly Targeting Pin1CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesisIdentification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell CarcinomaProtein kinase A regulates MYC protein through transcriptional and post-translational mechanisms in a catalytic subunit isoform-specific manner.Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes.Data recovery and integration from public databases uncovers transformation-specific transcriptional downregulation of cAMP-PKA pathway-encoding genes.Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcriptionHN1 contributes to migration, invasion, and tumorigenesis of breast cancer by enhancing MYC activity.MYC association with cancer risk and a new model of MYC-mediated repression.Cytoplasmic expression of C-MYC protein is associated with risk stratification of mantle cell lymphoma.Functional interaction between type III-secreted protein IncA of Chlamydophila psittaci and human G3BP1Ras activity regulates cyclin E degradation by the Fbw7 pathway.Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancerMechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expressionMultiple loci with different cancer specificities within the 8q24 gene desert.High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycleYou Don't Muck with MYCGain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemiaDecorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis.Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland.Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene.Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530.Inhibition of 5-lipoxygenase selectively triggers disruption of c-Myc signaling in prostate cancer cells.Troglitazone suppresses c-Myc levels in human prostate cancer cells via a PPARγ-independent mechanismA therapeutic role for targeting c-Myc/Hif-1-dependent signaling pathways.Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis.MYC levels govern hematopoietic tumor type and latency in transgenic miceTransformation by E1A oncoprotein involves ubiquitin-mediated proteolysis of the neuronal and tumor repressor REST in the nucleus.Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.E3 Ubiquitin Ligase RLIM Negatively Regulates c-Myc Transcriptional Activity and Restrains Cell ProliferationActivation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells.Strategies to Inhibit Myc and Their Clinical Applicability
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The life cycle of C-myc: from synthesis to degradation.
@ast
The life cycle of C-myc: from synthesis to degradation.
@en
type
label
The life cycle of C-myc: from synthesis to degradation.
@ast
The life cycle of C-myc: from synthesis to degradation.
@en
prefLabel
The life cycle of C-myc: from synthesis to degradation.
@ast
The life cycle of C-myc: from synthesis to degradation.
@en
P1433
P1476
The life cycle of C-myc: from synthesis to degradation.
@en
P2093
Rosalie C Sears
P304
P577
2004-09-05T00:00:00Z