Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance
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Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signalingMRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length controlThe role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint controlChemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cellsRole of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediatesA novel allele of fission yeast rad11 that causes defects in DNA repair and telomere length regulation.A kinase-independent role for the Rad3(ATR)-Rad26(ATRIP) complex in recruitment of Tel1(ATM) to telomeres in fission yeastThe fission yeast Rad32(Mre11)-Rad50-Nbs1 complex acts both upstream and downstream of checkpoint signaling in the S-phase DNA damage checkpointFission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage.ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1.NBS1 plays a synergistic role with telomerase in the maintenance of telomeres in Arabidopsis thaliana.A postsynaptic role for Rhp55/57 that is responsible for cell death in Deltarqh1 mutants following replication arrest in Schizosaccharomyces pombeMutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activityConserved and nonconserved proteins for meiotic DNA breakage and repair in yeasts.Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres.Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeastIdentification and characterization of a novel gene encoding the NBS1 protein in Pyricularia oryzae.The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA-Dependent Tel1 Activation.Molecular basis of ataxia telangiectasia and related diseases.Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex.Meiotic DNA double-strand break repair requires two nucleases, MRN and Ctp1, to produce a single size class of Rec12 (Spo11)-oligonucleotide complexes.Rad62 protein functionally and physically associates with the smc5/smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast.Fission yeast Dna2 is required for generation of the telomeric single-strand overhangThe fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint.Break-induced loss of heterozygosity in fission yeast: dual roles for homologous recombination in promoting translocations and preventing de novo telomere addition.A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining.
P2860
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P2860
Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance
description
2003 nî lūn-bûn
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2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
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2003年论文
@zh-cn
name
Molecular characterization of ...... epair and telomere maintenance
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Molecular characterization of ...... epair and telomere maintenance
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type
label
Molecular characterization of ...... epair and telomere maintenance
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Molecular characterization of ...... epair and telomere maintenance
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prefLabel
Molecular characterization of ...... epair and telomere maintenance
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Molecular characterization of ...... epair and telomere maintenance
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P2093
P2860
P50
P1476
Molecular characterization of ...... epair and telomere maintenance
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P2093
Hideo Shinagawa
Kikuo Watanabe
Masaru Ueno
Tomofumi Nakazaki
Yufuko Akamatsu
P2860
P304
P356
10.1128/MCB.23.18.6553-6563.2003
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P577
2003-09-01T00:00:00Z