Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint.
about
Methylseleninic acid enhances paclitaxel efficacy for the treatment of triple-negative breast cancerLoss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosisThe DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitorCENP-V is required for centromere organization, chromosome alignment and cytokinesis.Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosisBubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis.Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndromeUBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exitMPS1-dependent mitotic BLM phosphorylation is important for chromosome stabilityMicrotubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied.Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint.Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fateDancing genomes: fungal nuclear positioningA positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidizationElucidation of the function of type 1 human methionine aminopeptidase during cell cycle progressionDido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stabilitySpindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochoreHURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture.DNA damage associated with mitosis and cytokinesis failureA novel microtubule inhibitor 4SC-207 with anti-proliferative activity in taxane-resistant cellsMitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells.Tumor treating fields perturb the localization of septins and cause aberrant mitotic exitCellular contractility requires ubiquitin mediated proteolysisSelective Aurora Kinase Inhibitors Identified Using a Taxol-Induced Checkpoint Sensitivity ScreenA Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly CheckpointCell cycle checkpoint in cancer: a therapeutically targetable double-edged swordPolar Ejection Forces Promote the Conversion from Lateral to End-on Kinetochore-Microtubule Attachments on Mono-oriented ChromosomesCell fusion induced by ERVWE1 or measles virus causes cellular senescenceDrosophila CENP-A mutations cause a BubR1-dependent early mitotic delay without normal localization of kinetochore componentsMolecular analysis of core kinetochore composition and assembly in Drosophila melanogasterStochastic competition between mechanistically independent slippage and death pathways determines cell fate during mitotic arrestA screen for selective killing of cells with chromosomal instability induced by a spindle checkpoint defectAurora-A kinase is essential for bipolar spindle formation and early developmentBrd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatinAurora kinase-A deficiency during skin development impairs cell division and stratificationImpaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear proteinOmcg1 is critically required for mitosis in rapidly dividing mouse intestinal progenitors and embryonic stem cells.ASAP, a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis
P2860
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P2860
Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Stuck in division or passing t ...... e spindle assembly checkpoint.
@ast
Stuck in division or passing t ...... e spindle assembly checkpoint.
@en
type
label
Stuck in division or passing t ...... e spindle assembly checkpoint.
@ast
Stuck in division or passing t ...... e spindle assembly checkpoint.
@en
prefLabel
Stuck in division or passing t ...... e spindle assembly checkpoint.
@ast
Stuck in division or passing t ...... e spindle assembly checkpoint.
@en
P1433
P1476
Stuck in division or passing t ...... e spindle assembly checkpoint.
@en
P2093
Conly L Rieder
Helder Maiato
P304
P356
10.1016/J.DEVCEL.2004.09.002
P407
P577
2004-11-01T00:00:00Z