Dissociating the centrosomal matrix protein AKAP450 from centrioles impairs centriole duplication and cell cycle progression. - Wikidata - wikimedia - TriplyDB

Dissociating the centrosomal matrix protein AKAP450 from centrioles impairs centriole duplication and cell cycle progression.

Dissociating the centrosomal matrix protein AKAP450 from centrioles impairs centriole duplication and cell cycle progression.

http://www.wikidata.org/entity/Q35941256

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Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex TSKS concentrates in spermatid centrioles during flagellogenesis Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130 Cyclin G2 is a centrosome-associated nucleocytoplasmic shuttling protein that influences microtubule stability and induces a p53-dependent cell cycle arrest Coiled-coil proteins facilitated the functional expansion of the centrosome AKAP9 is essential for spermatogenesis and sertoli cell maturation in mice Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity.Centrosome maturation requires YB-1 to regulate dynamic instability of microtubules for nucleus reassembly CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response.The arithmetic of centrosome biogenesis.Antizyme restrains centrosome amplification by regulating the accumulation of Mps1 at centrosomes Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.Steroidogenic Factor 1 (NR5A1) resides in centrosomes and maintains genomic stability by controlling centrosome homeostasis.A primary microcephaly protein complex forms a ring around parental centrioles.Preventing the degradation of mps1 at centrosomes is sufficient to cause centrosome reduplication in human cells.The Drosophila pericentrin-like protein is essential for cilia/flagella function, but appears to be dispensable for mitosis.AKAP9 regulates activation-induced retention of T lymphocytes at sites of inflammation PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome.The centrosome and cell proliferation.Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy The centrosome protein NEDD1 as a potential pharmacological target to induce cell cycle arrest.hPOC5 is a centrin-binding protein required for assembly of full-length centrioles.AKAP350 Is involved in the development of apical "canalicular" structures in hepatic cells HepG2.Pericentriolar material structure and dynamics.The centrosome-Golgi apparatus nexus Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle.Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells.Centrosomal AKAP350 modulates the G1/S transition CP250, a novel acidic coiled-coil protein of the Dictyostelium centrosome, affects growth, chemotaxis, and the nuclear envelope.The C-terminal region of A-kinase anchor protein 350 (AKAP350A) enables formation of microtubule-nucleation centers and interacts with pericentriolar proteins.Two-way traffic: centrosomes and the cell cycle.The GTPase RAN regulates multiple steps of the centrosome life cycle.

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P2860

Dissociating the centrosomal matrix protein AKAP450 from centrioles impairs centriole duplication and cell cycle progression.

http://www.wikidata.org/entity/Q35941256

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2003年论文

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2003年论文

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Dissociating the centrosomal m ...... on and cell cycle progression.

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Dissociating the centrosomal m ...... on and cell cycle progression.

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Dissociating the centrosomal m ...... on and cell cycle progression.

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Dissociating the centrosomal m ...... on and cell cycle progression.

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Dissociating the centrosomal m ...... on and cell cycle progression.

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Dissociating the centrosomal m ...... on and cell cycle progression.

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MBC.E02-09-0614

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Molecular Biology of the Cell

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Dissociating the centrosomal m ...... on and cell cycle progression.

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Annie Delouvée

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Danielle Rouillard

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Guy Keryer

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Michel Bornens

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Oliwia Witczak

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Wolfram A Kemmner

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P2860

NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1

Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin

Katanin, a microtubule-severing protein, is a novel AAA ATPase that targets to the centrosome using a WD40-containing subunit

A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.

Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.

Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

Differential subcellular localization of protein phosphatase-1 alpha, gamma1, and delta isoforms during both interphase and mitosis in mammalian cells

The spacer protein Spc110p targets calmodulin to the central plaque of the yeast spindle pole body.

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194891

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