Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide. - Wikidata - wikimedia - TriplyDB

Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide.

Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide.

http://www.wikidata.org/entity/Q35960841

about

RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes DNA demethylation and invasive cancer: implications for therapeutics Methylation-dependent gene silencing induced by interleukin 1beta via nitric oxide production The DNMT1 target recognition domain resides in the N terminus.DNA methyltransferases: a novel target for prevention and therapy.P15INK4b gene methylation and myelodysplastic syndromes.DNA methylation and cancer.Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells.Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.DNA methylation, chromatin inheritance, and cancer.Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.DNA methylation in genomic imprinting, development, and disease.Methylation and colorectal cancer.Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasiveness Suppression of TET1-dependent DNA demethylation is essential for KRAS-mediated transformation.Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases.6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1 Derepression of Cancer/testis antigens in cancer is associated with distinct patterns of DNA hypomethylation.Epigenetic cancer therapies: DNA methyltransferase inhibitors.Mallory-Denk Body (MDB) formation modulates Ufmylation expression epigenetically in alcoholic hepatitis (AH) and non-alcoholic steatohepatitis (NASH).DNA demethylating antineoplastic strategies: a comparative point of view Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice.An ultrasensitive high throughput screen for DNA methyltransferase 1-targeted molecular probes CHST11 gene expression and DNA methylation in breast cancer Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1.AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 mRNA stability Demethylation of DNA by decitabine in cancer chemotherapy.RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylation Therapeutic implications of DNA methylation.Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences.Modified oligonucleotides as bona fide antagonists of proteins interacting with DNA. Hairpin antagonists of the human DNA methyltransferase.Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis.DNA methyltransferase 1 knock down induces gene expression by a mechanism independent of DNA methylation and histone deacetylation.A potent cell-active allosteric inhibitor of murine DNA cytosine C5 methyltransferase.CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing.DNA methyltransferase 1 knockdown activates a replication stress checkpoint.Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.

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P2860

Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide.

http://www.wikidata.org/entity/Q35960841

description

1997 nî lūn-bûn

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1997年論文

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1997年论文

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1997年论文

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name

Inhibition of tumorigenesis by ...... ntisense oligodeoxynucleotide.

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Inhibition of tumorigenesis by ...... ntisense oligodeoxynucleotide.

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Proceedings of the National Academy of Sciences of the United States of America

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Inhibition of tumorigenesis by ...... ntisense oligodeoxynucleotide.

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A R MacLeod

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E von Hofe

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M Pinard

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M Szyf

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S Ramchandani

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P2860

p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3

DNA methylation and gene function

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

Inhibition of telomerase by G-quartet DNA structures.

Role of RNase H in hybrid-arrested translation by antisense oligonucleotides

The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia

De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines.

Nucleotide-sequence-specific de novo methylation in a somatic murine cell line.

CpG motifs in bacterial DNA trigger direct B-cell activation.

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684-689

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