Prevention of autoimmune diabetes by ectopic pancreatic β-cell expression of interleukin-35.
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Interleukin-35: Expanding Its Job ProfileFrom IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokinesToward beta cell replacement for diabetesThe modulation of endoplasmic reticulum stress by chemical chaperone upregulates immune negative cytokine IL-35 in apolipoprotein E-deficient miceInterleukin 35 may contribute to the loss of immunological self-tolerance in patients with primary immune thrombocytopenia.Plasma Levels of Interleukin 12 Family Cytokines and Their Relevant Cytokines in Adult Patients with Chronic Immune Thrombocytopenia before and after High-Dose Dexamethasome TreatmentTCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.IL-12 family cytokines: immunological playmakersCytokine-modulating strategies and newer cytokine targets for arthritis therapy.Decreased plasma IL-35 levels are related to the left ventricular ejection fraction in coronary artery diseases.Tumor-derived IL-35 promotes tumor growth by enhancing myeloid cell accumulation and angiogenesisIL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases.Epstein-Barr virus-induced gene 3-deficiency leads to impaired antitumor T-cell responses and accelerated tumor growth.Interleukin-35 administration counteracts established murine type 1 diabetes--possible involvement of regulatory T cells.Interleukin-35 Limits Anti-Tumor Immunity.IL-Y, a synthetic member of the IL-12 cytokine family, suppresses the development of type 1 diabetes in NOD miceRodent models for investigating the dysregulation of immune responses in type 1 diabetes.Elevated serum IL-35 and increased expression of IL-35-p35 or -EBI3 in CD4(+)CD25(+) T cells in patients with active tuberculosis.Thymic versus induced regulatory T cells - who regulates the regulators?Assessing the role of IL-35 in colorectal cancer progression and prognosis.Interleukin-35-Producing CD8α+ Dendritic Cells Acquire a Tolerogenic State and Regulate T Cell Function.Interleukin 35 Polymorphisms Are Associated with Decreased Risk of Premature Coronary Artery Disease, Metabolic Parameters, and IL-35 Levels: The Genetics of Atherosclerotic Disease (GEA) Study.Interleukin 35: a key mediator of suppression and the propagation of infectious tolerance.Bioengineering heterodimeric cytokines: turning promiscuous proteins into therapeutic agents.Advances in the cellular immunological pathogenesis of type 1 diabetesIL-35: a potential therapeutic target for controlling hepatitis B virus infection.IL-35 and Autoimmunity: a Comprehensive Perspective.β-cell-specific IL-35 therapy suppresses ongoing autoimmune diabetes in NOD mice.Interluekin-35 in Asthma and Its Potential as an Effective Therapeutic Agent.IL-35, as a newly proposed homeostasis-associated molecular pattern, plays three major functions including anti-inflammatory initiator, effector, and blocker in cardiovascular diseases.Role of immune system modulation in prevention of type 1 diabetes mellitus.Gene Expression and Antiviral Activity of Interleukin-35 in Response to Influenza A Virus Infection.[Current Research of the Roles of IL-35 in Tumor Progression].Interleukin-35 on B cell and T cell induction and regulation.Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity.Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas.Interleukin-12p35 Knock Out Aggravates Doxorubicin-Induced Cardiac Injury and Dysfunction by Aggravating the Inflammatory Response, Oxidative Stress, Apoptosis and Autophagy in Mice
P2860
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P2860
Prevention of autoimmune diabetes by ectopic pancreatic β-cell expression of interleukin-35.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Prevention of autoimmune diabe ...... expression of interleukin-35.
@ast
Prevention of autoimmune diabe ...... expression of interleukin-35.
@en
type
label
Prevention of autoimmune diabe ...... expression of interleukin-35.
@ast
Prevention of autoimmune diabe ...... expression of interleukin-35.
@en
prefLabel
Prevention of autoimmune diabe ...... expression of interleukin-35.
@ast
Prevention of autoimmune diabe ...... expression of interleukin-35.
@en
P2093
P2860
P356
P1433
P1476
Prevention of autoimmune diabe ...... expression of interleukin-35.
@en
P2093
Amanda R Burton
Ashley H Castellaw
Dario A A Vignali
Greig P Lennon
P2860
P304
P356
10.2337/DB11-0784
P407
P577
2012-03-16T00:00:00Z