Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response.
about
Conservation and variability of dengue virus proteins: implications for vaccine designThe relationship between predicted peptide-MHC class II affinity and T-cell activation in a HLA-DRbeta1*0401 transgenic mouse modelAssociation of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and menConservation and diversity of influenza A H1N1 HLA-restricted T cell epitope candidates for epitope-based vaccines.Predominant selection of T cells specific for the glycosylated collagen type II epitope (263-270) in humanized transgenic mice and in rheumatoid arthritisDendritic cell mediated delivery of plasmid DNA encoding LAMP/HIV-1 Gag fusion immunogen enhances T cell epitope responses in HLA DR4 transgenic miceHuman risk allele HLA-DRB1*0405 predisposes class II transgenic Ab0 NOD mice to autoimmune pancreatitis.Humanized mice as a model for rheumatoid arthritis.DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype.A single functional group substitution in c5a breaks B cell and T cell tolerance and protects against experimental arthritis.Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis.Mice lacking all conventional MHC class II genes.T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin.West Nile virus T-cell ligand sequences shared with other flaviviruses: a multitude of variant sequences as potential altered peptide ligandsIdentification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.The T cell response of HLA-DR transgenic mice to human myelin basic protein and other antigens in the presence and absence of human CD4.HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritisCrystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice.Synthetic amino acid copolymers that bind to HLA-DR proteins and inhibit type II collagen-reactive T cell clones.Comparative analysis of collagen type II-specific immune responses during development of collagen-induced arthritis in two B10 mouse strains.Design of peptide immunotherapies for MHC Class-II-associated autoimmune disorders.Antibodies to a single, conserved epitope in Anopheles APN1 inhibit universal transmission of Plasmodium falciparum and Plasmodium vivax malaria.HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis.HLA transgenic mice as humanized mouse models of disease and immunity.Humanized transgenic mice expressing HLA DR4-DQ3 haplotype: reconstitution of phenotype and HLA-restricted T-cell responses.T cell responses to a human cartilage autoantigen in the context of rheumatoid arthritis-associated and nonassociated HLA-DR4 alleles.A humanized HLA-DR4 mouse model for autoimmune myocarditis.
P2860
Q24288762-D4ED1DC6-D93D-4399-97D6-CDED8F5C747BQ24795875-1B3888F6-B3D2-4434-9C71-F3A3244318F3Q24807019-597FCBC9-1E5D-4797-873A-7A404F88B9F1Q30384675-426A9D3B-E0DE-48EF-A949-4C6BCD14A2BAQ31089923-573BFA5B-B281-4F74-9ECD-8719DCCD9E35Q33522216-F809AEBA-EDA0-43EE-8CEE-BE31B0E0D978Q33987557-5D134B5B-E94B-4D06-8C13-911317F99625Q34731162-E0169C0C-2E4B-443D-8231-6681FEF6E8F0Q34984492-1AB9165D-73F7-4522-875E-8D3E6CCFB44AQ34998962-69F2877B-79E9-4509-9BDA-A425ACAEE297Q35080702-D4F78875-A92B-4B24-8493-5678AA2E34ABQ35620743-96F3D62B-10BF-41E8-87E4-2ECC32EC25D6Q36011042-E52B2C44-8C81-488B-8E65-E14729859E4EQ36155428-34AFE65A-E8DB-476A-AA78-A58999021C4EQ36301274-C69B897E-6EA0-45F0-861B-9D4F03D3EAACQ36364563-D21ABBAD-2569-4654-B4D4-F92C49CBDD1AQ36366088-A5C24247-363D-41FE-A70C-BD0DA1D00FD4Q36476612-4203A2DE-949F-40E8-B11F-215EECFD3D8EQ36498837-6E342A54-7428-4D4C-A31B-97861D74A812Q36526075-DDFEAA0E-60C0-43B6-9D44-F3A12D7492F8Q36907623-0136CC4E-5D42-4283-8CF0-F466C763F531Q37353611-9F88A286-F26D-4E41-BEEA-7F21B9195541Q37546481-35FC22FE-E616-4C3C-BE9E-3AA0FB5612F9Q38357177-245E47D7-0E45-4F31-9520-AD9FEB540428Q39799339-74C9EFDE-3D8F-4A22-9DE2-C0461B17CA24Q40237052-990C1BCD-CBDF-4E54-9CC9-3A0608CF7A51Q41678690-B040FB75-F085-4159-837F-D6F42F9BA999Q41919872-1A7A6603-CF6D-49DA-ACCC-982225937EA7
P2860
Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Expression of HLA-DR4 and huma ...... DR-restricted immune response.
@ast
Expression of HLA-DR4 and huma ...... DR-restricted immune response.
@en
type
label
Expression of HLA-DR4 and huma ...... DR-restricted immune response.
@ast
Expression of HLA-DR4 and huma ...... DR-restricted immune response.
@en
prefLabel
Expression of HLA-DR4 and huma ...... DR-restricted immune response.
@ast
Expression of HLA-DR4 and huma ...... DR-restricted immune response.
@en
P2093
P2860
P356
P1476
Expression of HLA-DR4 and huma ...... DR-restricted immune response.
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.13.6151
P407
P577
1994-06-01T00:00:00Z