Melanosome maturation defect in Rab38-deficient retinal pigment epithelium results in instability of immature melanosomes during transient melanogenesis.
about
BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organellesThe tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesisInterpreting melanin-based coloration through deep time: a critical reviewRab and Arf proteins in genetic diseasesInteraction with the effector dynamin-related protein 1 (Drp1) is an ancient function of Rab32 subfamily proteinsBLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factorVarp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytesThe ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cellsPigmented anatomy in Carboniferous cyclostomes and the evolution of the vertebrate eyeNotochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis.BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriersCell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes.The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice.Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes.Phagosome maturation during endosome interaction revealed by partial rhodopsin processing in retinal pigment epithelium.Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomesRab GTPase prenylation hierarchy and its potential role in choroideremia diseaseRegulation of the human tyrosinase gene in retinal pigment epithelium cells: the significance of transcription factor orthodenticle homeobox 2 and its polymorphic binding siteTargeting protein-trafficking pathways alters melanoma treatment sensitivity.Semi-automated analysis of organelle movement and membrane content: understanding rab-motor complex transport functionMERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors.Mechanisms of protein delivery to melanosomes in pigment cells.Modeling disease mutations by gene targeting in one-cell mouse embryosDirect production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides.A gene expression profile of the developing human retinal pigment epithelium.PMEL: a pigment cell-specific model for functional amyloid formationA mutation in Rab38 small GTPase causes abnormal lung surfactant homeostasis and aberrant alveolar structure in mice.BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells.Lysosome-related organelles: unusual compartments become mainstream.Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.A novel anti-microbial function for a familiar Rab GTPase.Study of Exosomes Shed New Light on Physiology of Amyloidogenesis.Rab proteins as regulators of lipid droplet formation and lipolysis.AAV-mediated tyrosinase gene transfer restores melanogenesis and retinal function in a model of oculo-cutaneous albinism type I (OCA1).Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL.The retinal pigment epithelium of the eye regulates the development of scleral cartilage.Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation.Fibroblast growth factor signalling controls nervous system patterning and pigment cell formation in Ciona intestinalis.Expression of OA1 limits the fusion of a subset of MVBs with lysosomes - a mechanism potentially involved in the initial biogenesis of melanosomes.HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38
P2860
Q24315003-23CE2373-70EC-431B-8BF9-69CC44E80FE8Q24338990-158B5646-E6B3-4576-B511-5FB9F141BE71Q26796363-E2D51F12-81EB-4F24-8E9A-BDED8BD2EB91Q26862704-25E4A072-B999-4E57-83B4-20DA4D83EA44Q28115441-E7244812-D13C-43E8-A447-470D797AD25CQ28117259-5595E521-BA00-4E11-91B3-A072B4E2BFF2Q28505813-9CDBF1E3-A6C0-4AB5-AE30-9125EB93BEB0Q28589486-946B11B1-05FF-43EA-A912-21B06CCD7715Q28596189-0B7AF4BC-90EF-4AF5-9996-41114F86DCBDQ30417308-9233BB48-7CB0-4974-AE3F-60AA6B6EF74EQ30793347-8664408B-CC23-4F0F-A6BB-40D3C8B962EBQ33613085-F9E0208E-6441-42F7-BF70-218460E3EF41Q33786878-27391D9C-4D2B-46BE-BB22-EFBECD4BD51FQ33810200-61BA5407-6917-45CC-8ECD-4B72100EA925Q34112740-4F91D0FE-1E95-4FEC-8ED2-47B5F8AA38E5Q34580378-F0675541-8BF3-4B0B-A3FE-8B2404D92783Q35072549-0DF46E99-FA12-42D3-93BA-F4ADFDF08D68Q35673412-AA8A8802-7279-4344-B612-E6881BBA84BEQ35673847-EA2BBA67-46A7-4C9D-AE1C-2EB6129933F4Q35690713-8224B9FE-B038-4D1A-9632-506642E4B9E3Q35748292-5ED4C2B8-1801-423B-BF2B-1AB21551D69DQ35936316-87FEBECE-E91A-4673-87A3-9F9C2C84A5C8Q36066204-75C4D2F8-63E7-401A-9B2F-1CB5461E0ECCQ36673358-5B76035E-6241-4FD9-BB13-21CA87E968BFQ36676689-89106163-3037-4FDA-9D65-A8E7CB09C76AQ36788313-2EFC8EE4-ACBB-47E4-AD88-C3DCF0D55293Q36943045-A06422E0-E149-4AB3-99DB-A92DF6C67490Q36967843-472DD271-6021-4A5D-A444-77FCEFFE3F8DQ37060715-B023DDFA-7EA0-4856-B7B0-B7BB79DDD94CQ38068089-BEE1FF07-EA59-4932-A414-12176DFF31DDQ38169882-36F034AD-3944-4375-830C-58313E0F03D3Q38777380-5DE2ED72-D37B-452A-8969-5EE56129B44EQ38907192-6F8CDF8B-394A-4ED8-869C-D64E5D69559BQ39510173-ADEA674F-6C01-4D35-8D35-B13136A94AC0Q41818361-9296DC7F-EB7D-49A1-8F3C-6D6812AFB11EQ42371766-B477AB96-8944-47DA-B8D8-CBAFD593FD35Q42386681-937E2167-9F68-490F-BDCC-99EBBD31E293Q42878385-3E3B5369-159B-4906-A1F4-59A33F256DBFQ42906442-4B40DB03-5FE3-4597-B5B8-00CAEBEC34D2Q50299999-C35F36E7-134B-4802-BA24-7D60DBA5E061
P2860
Melanosome maturation defect in Rab38-deficient retinal pigment epithelium results in instability of immature melanosomes during transient melanogenesis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Melanosome maturation defect i ...... uring transient melanogenesis.
@ast
Melanosome maturation defect i ...... uring transient melanogenesis.
@en
type
label
Melanosome maturation defect i ...... uring transient melanogenesis.
@ast
Melanosome maturation defect i ...... uring transient melanogenesis.
@en
prefLabel
Melanosome maturation defect i ...... uring transient melanogenesis.
@ast
Melanosome maturation defect i ...... uring transient melanogenesis.
@en
P2860
P356
P1476
Melanosome maturation defect i ...... uring transient melanogenesis.
@en
P2093
Christina Wasmeier
Vanda S Lopes
P2860
P304
P356
10.1091/MBC.E07-03-0268
P577
2007-08-01T00:00:00Z