Receptors coupled to heterotrimeric G proteins of the G12 family.
about
PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressorGalpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeletonNovel cannabinoid receptorsG-protein-coupled receptor agonists activate endogenous phospholipase Cepsilon and phospholipase Cbeta3 in a temporally distinct mannerAntagonist minigenes identify genes regulated by parathyroid hormone through G protein-selective and G protein co-regulated mechanisms in osteoblastic cellsPulsatile equibiaxial stretch inhibits thrombin-induced RhoA and NF-kappaB activation.Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13.Prediction of the coupling specificity of GPCRs to four families of G-proteins using hidden Markov models and artificial neural networks.Polyamines transduce the nongenomic, androgen-induced calcium sensitization in intestinal smooth muscleCCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini.G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signalingPolycystin-1 protein level determines activity of the Galpha12/JNK apoptosis pathway.Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.G12 signaling through c-Jun NH2-terminal kinase promotes breast cancer cell invasion.The systematic annotation of the three main GPCR families in Reactome.G Protein and β-arrestin signaling bias at the ghrelin receptor.The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis.Heterotrimeric G-protein alpha-12 (Gα12) subunit promotes oral cancer metastasis.Heterotrimeric Gi proteins link Hedgehog signaling to activation of Rho small GTPases to promote fibroblast migration.A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression.The alpha subunit of the G protein G13 regulates activity of one or more Gli transcription factors independently of smoothened.Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13Gα12 activation in podocytes leads to cumulative changes in glomerular collagen expression, proteinuria and glomerulosclerosis.Role of Galpha12 and Galpha13 as novel switches for the activity of Nrf2, a key antioxidative transcription factor.Stimulation of Dopamine D3 Receptor Attenuates Renal Ischemia-Reperfusion Injury via Increased Linkage With Gα12.Genetic variation in G-protein-coupled receptors--consequences for G-protein-coupled receptors as drug targets.Heterotrimeric G-proteins: a short history.Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway.Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses.RhoGEF12 controls cardiac remodeling by integrating G protein- and integrin-dependent signaling cascades.Central role of Gq in the hypertrophic signal transduction of angiotensin II in vascular smooth muscle cells.G alpha12 is targeted to the mitochondria and affects mitochondrial morphology and motility.Regulation of thymus-dependent and thymus-independent production of immunoglobulin G subclasses by Galpha12 and Galpha13.Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors.Regulation of heterotrimeric G protein signaling in airway smooth muscle.Endothelial nitric oxide synthase inhibits G12/13 and rho-kinase activated by the angiotensin II type-1 receptor: implication in vascular migrationG protein-coupled receptors go extracellular: RhoA integrates the integrins.Regulation and physiological functions of G12/13-mediated signaling pathways.P2Y5 is a G(alpha)i, G(alpha)12/13 G protein-coupled receptor activated by lysophosphatidic acid that reduces intestinal cell adhesion.
P2860
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P2860
Receptors coupled to heterotrimeric G proteins of the G12 family.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Receptors coupled to heterotrimeric G proteins of the G12 family.
@ast
Receptors coupled to heterotrimeric G proteins of the G12 family.
@en
type
label
Receptors coupled to heterotrimeric G proteins of the G12 family.
@ast
Receptors coupled to heterotrimeric G proteins of the G12 family.
@en
prefLabel
Receptors coupled to heterotrimeric G proteins of the G12 family.
@ast
Receptors coupled to heterotrimeric G proteins of the G12 family.
@en
P1476
Receptors coupled to heterotrimeric G proteins of the G12 family.
@en
P2093
David R Manning
Natalia A Riobo
P304
P356
10.1016/J.TIPS.2005.01.007
P577
2005-03-01T00:00:00Z