The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis. - Wikidata - wikimedia - TriplyDB

The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis.

The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis.

http://www.wikidata.org/entity/Q34650253

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Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.Tre1 GPCR initiates germ cell transepithelial migration by regulating Drosophila melanogaster E-cadherin A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells Extra-nuclear signaling of progesterone receptor to breast cancer cell movement and invasion through the actin cytoskeleton.Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55.RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells.Growth inhibition of human breast carcinoma cells by overexpression of regulator of G-protein signaling 4.Breast cancer cell invasion mediated by Gα12 signaling involves expression of interleukins-6 and -8, and matrix metalloproteinase-2.Gbetagamma signaling promotes breast cancer cell migration and invasion.Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion.G12 signaling through c-Jun NH2-terminal kinase promotes breast cancer cell invasion.The thromboxane synthase and receptor signaling pathway in cancer: an emerging paradigm in cancer progression and metastasis.Activation of Rap1 promotes prostate cancer metastasis Novel somatic mutations in heterotrimeric G proteins in melanoma Heterotrimeric G-protein alpha-12 (Gα12) subunit promotes oral cancer metastasis.Gα₁₂ drives invasion of oral squamous cell carcinoma through up-regulation of proinflammatory cytokines A critical role of Gbetagamma in tumorigenesis and metastasis of breast cancer.MicroRNA-31 controls G protein alpha-13 (GNA13) expression and cell invasion in breast cancer cells Prostaglandin E2 regulates renal cell carcinoma invasion through the EP4 receptor-Rap GTPase signal transduction pathway.Gastrin-stimulated Gα13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells.Cancer Cell Invasion in Three-dimensional Collagen Is Regulated Differentially by Gα13 Protein and Discoidin Domain Receptor 1-Par3 Protein Signaling Low expression of GNAI3 predicts poor prognosis in patients with HCC.MicroRNA-182 and microRNA-200a control G-protein subunit α-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells.Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling.Why does melanoma metastasize into the brain? Genes with pleiotropic effects might be the key Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.Synthetic and natural iron chelators: therapeutic potential and clinical use Breast cancer migration and invasion depend on proteasome degradation of regulator of G-protein signaling 4.Regulation and physiological functions of G12/13-mediated signaling pathways.Regulation of RhoGEF proteins by G12/13-coupled receptors.Role of G12 proteins in oncogenesis and metastasis Site-specific metastasis formation: chemokines as regulators of tumor cell adhesion, motility and invasion.Heterotrimeric G proteins and apoptosis: intersecting signaling pathways leading to context dependent phenotypes Gα12 structural determinants of Hsp90 interaction are necessary for serum response element-mediated transcriptional activation.PAR1 plays a role in epithelial malignancies: transcriptional regulation and novel signaling pathway.G12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery.Gα12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinoma.

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The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis.

http://www.wikidata.org/entity/Q34650253

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2006 nî lūn-bûn

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2006年の論文

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2006年論文

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The G12 family of heterotrimer ...... ancer invasion and metastasis.

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The G12 family of heterotrimer ...... ancer invasion and metastasis.

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The G12 family of heterotrimer ...... ancer invasion and metastasis.

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The G12 family of heterotrimer ...... ancer invasion and metastasis.

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The G12 family of heterotrimer ...... ancer invasion and metastasis.

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The G12 family of heterotrimer ...... ancer invasion and metastasis.

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The G12 family of heterotrimer ...... ancer invasion and metastasis.

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The G12 family of heterotrimer ...... ancer invasion and metastasis.

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The G12 family of heterotrimer ...... ancer invasion and metastasis.

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Proceedings of the National Academy of Sciences of the United States of America

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The G12 family of heterotrimer ...... ancer invasion and metastasis.

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Benjamin J Moeller

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Channing J Der

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Juhi Juneja

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Mark W Dewhirst

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Michelle A Booden

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Patrick J Casey

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Patrick Kelly

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Timothy A Fields

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Yehia Daaka

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P2860

Involvement of chemokine receptors in breast cancer metastasis

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

Thrombin receptor overexpression in malignant and physiological invasion processes

G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunits

Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF

CXCR4 regulates growth of both primary and metastatic breast cancer

Dissemination and growth of cancer cells in metastatic sites

RHO-GTPases and cancer

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