A method for prediction of the locations of linker regions within large multifunctional proteins, and application to a type I polyketide synthase.
about
Aflatoxin and deconstruction of type I, iterative polyketide synthase functionStructural basis for biosynthetic programming of fungal aromatic polyketide cyclizationStructure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesisConvergent biosynthetic pathways to β-lactam antibioticsCharacterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreusMultiresolution analysis uncovers hidden conservation of properties in structurally and functionally similar proteins.ASMPKS: an analysis system for modular polyketide synthasesInsights into the biosynthesis of 12-membered resorcylic acid lactones from heterologous production in Saccharomyces cerevisiae.Structural enzymology of polyketide synthases.Cyclization of aromatic polyketides from bacteria and fungiClassification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains.Recent advancements in the biosynthetic mechanisms for polyketide-derived mycotoxins.Demonstration of starter unit interprotein transfer from a fatty acid synthase to a multidomain, nonreducing polyketide synthase.Solution structure of the tandem acyl carrier protein domains from a polyunsaturated fatty acid synthase reveals beads-on-a-string configuration.Cloning and characterization of the gene cluster required for beauvericin biosynthesis in Fusarium proliferatum.Unraveling polyketide synthesis in members of the genus AspergillusIdentification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthaseThe enzymology of combinatorial biosynthesis.The rhodanese domain of ThiI is both necessary and sufficient for synthesis of the thiazole moiety of thiamine in Salmonella entericaNew insights into the formation of fungal aromatic polyketides.Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical "starter-unit effect".Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases.Starter unit specificity directs genome mining of polyketide synthase pathways in fungi.Bioinformatical analysis of the sequences, structures and functions of fungal polyketide synthase product template domains.Starter unit flexibility for engineered product synthesis by the nonreducing polyketide synthase PksAInterrogation of global active site occupancy of a fungal iterative polyketide synthase reveals strategies for maintaining biosynthetic fidelity.iPDA: integrated protein disorder analyzer.Engineering of an "unnatural" natural product by swapping polyketide synthase domains in Aspergillus nidulansAnalysis of the cercosporin polyketide synthase CTB1 reveals a new fungal thioesterase functionCharacterization of a fungal thioesterase having Claisen cyclase and deacetylase activities in melanin biosynthesis.A polyketide macrolactone synthase from the filamentous fungus Gibberella zeaeIn vitro reconstitution and substrate specificity of a lantibiotic protease.Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli.Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans.Engineered fungal polyketide biosynthesis in Pichia pastoris: a potential excellent host for polyketide production.Rational domain swaps reveal insights about chain length control by ketosynthase domains in fungal nonreducing polyketide synthases.A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases.Convergent strategies in biosynthesis.Synthetic biological approaches to natural product biosynthesis.The structural role of the carrier protein--active controller or passive carrier.
P2860
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P2860
A method for prediction of the locations of linker regions within large multifunctional proteins, and application to a type I polyketide synthase.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
A method for prediction of the ...... a type I polyketide synthase.
@ast
A method for prediction of the ...... a type I polyketide synthase.
@en
type
label
A method for prediction of the ...... a type I polyketide synthase.
@ast
A method for prediction of the ...... a type I polyketide synthase.
@en
prefLabel
A method for prediction of the ...... a type I polyketide synthase.
@ast
A method for prediction of the ...... a type I polyketide synthase.
@en
P2860
P1476
A method for prediction of the ...... o a type I polyketide synthase
@en
P2093
Craig A Townsend
Daniel W Udwary
P2860
P304
P356
10.1016/S0022-2836(02)00972-5
P407
P577
2002-10-01T00:00:00Z