Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription.
about
VprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelityRAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombinationCharacterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell linesGradient of E2A activity in B-cell development.B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5Defective nonhomologous end joining blocks B-cell development in FLT3/ITD miceFoxp1 is an essential transcriptional regulator of B cell developmentThe folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell developmentComplementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesisA tamoxifen inducible knock-in allele for investigation of E2A function.NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function.Analysis of mutations from SCID and Omenn syndrome patients reveals the central role of the Rag2 PHD domain in regulating V(D)J recombination.Functional replacement of the mouse E2A gene with a human HEB cDNA.The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly.Pro-B-cell-specific transcription and proapoptotic function of protein kinase CetaIn vivo conversion of BM plasmacytoid DC into CD11b+ conventional DC during virus infection.Murine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient miceRegulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility.Germ line transcription of the immunoglobulin heavy chain locus directs production of mu chain without VDJ.Evidence for failure of V(D)J recombination in bone marrow pre-B cells from X-linked agammaglobulinemia.Human antibodies from transgenic mice.Mouse lymphoid cell line selected to have high immunoglobulin promoter activity.Extensive gene-specific translational reprogramming in a model of B cell differentiation and Abl-dependent transformationBCL2A1a over-expression in murine hematopoietic stem and progenitor cells decreases apoptosis and results in hematopoietic transformation.Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors.Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency.Changes in histone acetylation are associated with differences in accessibility of V(H) gene segments to V-DJ recombination during B-cell ontogeny and developmentCis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.Ly49Q, a member of the Ly49 family that is selectively expressed on myeloid lineage cells and involved in regulation of cytoskeletal architectureEbf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiencyCancer predisposition and hematopoietic failure in Rad50(S/S) mice.Combined heterozygous loss of Ebf1 and Pax5 allows for T-lineage conversion of B cell progenitors.Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemiaRegulation of activation and recombination of the murine Igkappa locus.VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection.Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments.CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability.DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AIDFunction and control of recombination-activating gene activity.
P2860
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P2860
Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Virus-transformed pre-B cells ...... arrangement and transcription.
@ast
Virus-transformed pre-B cells ...... arrangement and transcription.
@en
type
label
Virus-transformed pre-B cells ...... arrangement and transcription.
@ast
Virus-transformed pre-B cells ...... arrangement and transcription.
@en
prefLabel
Virus-transformed pre-B cells ...... arrangement and transcription.
@ast
Virus-transformed pre-B cells ...... arrangement and transcription.
@en
P2093
P2860
P356
P1476
Virus-transformed pre-B cells ...... arrangement and transcription.
@en
P2093
D Baltimore
L M Corcoran
M S Schlissel
P2860
P304
P356
10.1084/JEM.173.3.711
P407
P577
1991-03-01T00:00:00Z