(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity
about
Integrating the puzzle pieces: the current atomistic picture of phospholipid-G protein coupled receptor interactionsSphingosine 1-Phosphate Receptors: Do They Have a Therapeutic Potential in Cardiac Fibrosis?FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury.Protection of neuroblastoma Neuro2A cells from hypoxia-induced apoptosis by cyclic phosphatidic acid (cPA).Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system.FTY720 (Gilenya) phosphate selectivity of sphingosine 1-phosphate receptor subtype 1 (S1P1) G protein-coupled receptor requires motifs in intracellular loop 1 and transmembrane domain 2Sphingosine kinase inhibitors and cancer: seeking the golden sword of HerculesChemical evolution of autotaxin inhibitorsAntiobesity activity of a sphingosine 1-phosphate analogue FTY720 observed in adipocytes and obese mouse model.Mitigation of radiation injury by selective stimulation of the LPA(2) receptorVirtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions.Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity.3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: molecular modeling of chiral recognition by FPR2Targeting the sphingosine kinase/sphingosine 1-phosphate pathway in disease: review of sphingosine kinase inhibitors.Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.Transcriptional modulation of SLC26A3 (DRA) by sphingosine-1-phosphate.Design, Synthesis, and Anti-leukemic Activity of Stereochemically Defined Constrained Analogs of FTY720 (Gilenya).Sphingosine 1-phosphate signalling in cancer.Design, synthesis, and preliminary cardioprotective effect evaluation of danshensu derivatives.Effect of sphingosine kinase modulators on interleukin-1β release, sphingosine 1-phosphate receptor 1 expression and experimental autoimmune encephalomyelitis.Pleiotropic effects of sphingosine-1-phosphate signaling to control human chorionic mesenchymal stem cell physiology.
P2860
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P2860
(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
(S)-FTY720-vinylphosphonate, a ...... nd inhibits autotaxin activity
@ast
(S)-FTY720-vinylphosphonate, a ...... nd inhibits autotaxin activity
@en
type
label
(S)-FTY720-vinylphosphonate, a ...... nd inhibits autotaxin activity
@ast
(S)-FTY720-vinylphosphonate, a ...... nd inhibits autotaxin activity
@en
prefLabel
(S)-FTY720-vinylphosphonate, a ...... nd inhibits autotaxin activity
@ast
(S)-FTY720-vinylphosphonate, a ...... nd inhibits autotaxin activity
@en
P2093
P2860
P1433
P1476
(S)-FTY720-vinylphosphonate, a ...... nd inhibits autotaxin activity
@en
P2093
Abby L Parrill
Chaode Sun
Daniel L Baker
Gabor Tigyi
Gyöngyi N Kiss
Jianxiong Liu
Kimiko Murakami-Murofushi
Mari Gotoh
Nigel J Pyne
Robert Bittman
P2860
P304
P356
10.1016/J.CELLSIG.2010.05.023
P577
2010-06-04T00:00:00Z