Characterization of a Chlamydomonas insertional mutant that disrupts flagellar central pair microtubule-associated structures.
about
Insertional mutation of the murine kisimo locus caused a defect in spermatogenesisKtu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins.The 9 + 2 axoneme anchors multiple inner arm dyneins and a network of kinases and phosphatases that control motilityLocalization of calmodulin and dynein light chain LC8 in flagellar radial spokesBend propagation drives central pair rotation in Chlamydomonas reinhardtii flagella.Mammalian axoneme central pair complex proteins: Broader roles revealed by gene knockout phenotypesODA16 aids axonemal outer row dynein assembly through an interaction with the intraflagellar transport machineryPcdp1 is a central apparatus protein that binds Ca(2+)-calmodulin and regulates ciliary motilityMutations in Hydin impair ciliary motility in miceDeficiency of SPAG16L causes male infertility associated with impaired sperm motilityDisruption of the A-kinase anchoring domain in flagellar radial spoke protein 3 results in unregulated axonemal cAMP-dependent protein kinase activity and abnormal flagellar motilityChlamydomonas mutants display reversible deficiencies in flagellar beating and axonemal assembly.The structural heterogeneity of radial spokes in cilia and flagella is conserved.Analyses of functional domains within the PF6 protein of the central apparatus reveal a role for PF6 sub-complex members in regulating flagellar beat frequencyThe N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes.Conserved structural motifs in the central pair complex of eukaryotic flagella.Mechanosignaling between central apparatus and radial spokes controls axonemal dynein activityRegulation of flagellar dynein activity by a central pair kinesin.The Chlamydomonas PF6 locus encodes a large alanine/proline-rich polypeptide that is required for assembly of a central pair projection and regulates flagellar motilityDimeric novel HSP40 is incorporated into the radial spoke complex during the assembly process in flagellaATP production in Chlamydomonas reinhardtii flagella by glycolytic enzymes.ODA16p, a Chlamydomonas flagellar protein needed for dynein assembly3D structure of eukaryotic flagella in a quiescent state revealed by cryo-electron tomography.Asymmetry of the central apparatus defines the location of active microtubule sliding in Chlamydomonas flagellaSpeculations on the evolution of 9+2 organelles and the role of central pair microtubulesCpc1, a Chlamydomonas central pair protein with an adenylate kinase domain.Molecular map of the Chlamydomonas reinhardtii nuclear genomeRegulation of ciliary motility: conserved protein kinases and phosphatases are targeted and anchored in the ciliary axonemeAn axonemal PP2A B-subunit is required for PP2A localization and flagellar motility.Space-dependent formation of central pair microtubules and their interactions with radial spokesThe Pcdp1 complex coordinates the activity of dynein isoforms to produce wild-type ciliary motilityThe radial spokes and central apparatus: mechano-chemical transducers that regulate flagellar motilityChlamydomonas flagellar outer row dynein assembly protein ODA7 interacts with both outer row and I1 inner row dyneinsRSPH3 Mutations Cause Primary Ciliary Dyskinesia with Central-Complex Defects and a Near Absence of Radial SpokesChlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility.A FAP46 mutant provides new insights into the function and assembly of the C1d complex of the ciliary central apparatus.A flagellar A-kinase anchoring protein with two amphipathic helices forms a structural scaffold in the radial spoke complex.Dimeric heat shock protein 40 binds radial spokes for generating coupled power strokes and recovery strokes of 9 + 2 flagella.PF19 encodes the p60 catalytic subunit of katanin and is required for assembly of the flagellar central apparatus in ChlamydomonasPF15p is the chlamydomonas homologue of the Katanin p80 subunit and is required for assembly of flagellar central microtubules.
P2860
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P2860
Characterization of a Chlamydomonas insertional mutant that disrupts flagellar central pair microtubule-associated structures.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Characterization of a Chlamydo ...... otubule-associated structures.
@ast
Characterization of a Chlamydo ...... otubule-associated structures.
@en
type
label
Characterization of a Chlamydo ...... otubule-associated structures.
@ast
Characterization of a Chlamydo ...... otubule-associated structures.
@en
prefLabel
Characterization of a Chlamydo ...... otubule-associated structures.
@ast
Characterization of a Chlamydo ...... otubule-associated structures.
@en
P2860
P356
P1476
Characterization of a Chlamydo ...... otubule-associated structures.
@en
P2093
D R Mitchell
P2860
P304
P356
10.1083/JCB.144.2.293
P407
P577
1999-01-01T00:00:00Z