Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site.
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Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regionsIgH chain class switch recombination: mechanism and regulationRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeLoss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis.R loops stimulate genetic instability of CTG.CAG repeats.Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions.AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants.A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expressionStrong transcription blockage mediated by R-loop formation within a G-rich homopurine-homopyrimidine sequence localized in the vicinity of the promoter.DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal.Role of transcript and interplay between transcription and replication in triplet-repeat instability in mammalian cells.Anchoring nascent RNA to the DNA template could interfere with transcriptionPNA binding to the non-template DNA strand interferes with transcription, suggesting a blockage mechanism mediated by R-loop formation.Role for RNA:DNA hybrids in origin-independent replication priming in a eukaryotic system.Complexities due to single-stranded RNA during antibody detection of genomic rna:dna hybrids.Quantitative model of R-loop forming structures reveals a novel level of RNA-DNA interactome complexity.Effect of CpG dinucleotides within IgH switch region repeats on immunoglobulin class switch recombination.Is Friedreich ataxia an epigenetic disorder?The Yin and Yang of R-loop biology.The repetitive portion of the Xenopus IgH Mu switch region mediates orientation-dependent class switch recombinationThe Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription.RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships.Transcription blockage by homopurine DNA sequences: role of sequence composition and single-strand breaks.GC skew is a conserved property of unmethylated CpG island promoters across vertebratesModulation of base excision repair of 8-oxoguanine by the nucleotide sequenceThe contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability.R-loops highlight the nucleus in ALS.RNA Polymerase Collision versus DNA Structural Distortion: Twists and Turns Can Cause Break FailureCanonical DNA Repair Pathways Influence R-Loop-Driven Genome Instability.The role of G-density in switch region repeats for immunoglobulin class switch recombination.The strength of an Ig switch region is determined by its ability to drive R loop formation and its number of WGCW sites.Excision of uracil from transcribed DNA negatively affects gene expression.Nascent Connections: R-Loops and Chromatin Patterning.Physiological functions of programmed DNA breaks in signal-induced transcription.The Role of Replication-Associated Repair Factors on R-Loops8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1.Initiation of Epstein-Barr virus lytic replication requires transcription and the formation of a stable RNA-DNA hybrid molecule at OriLyt.Endonuclease domain of the Drosophila melanogaster R2 non-LTR retrotransposon and related retroelements: a new model for transposition.The homologous recombination machinery modulates the formation of RNA-DNA hybrids and associated chromosome instability.R-Loop Formation In Trans at an AGGAG Repeat.
P2860
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P2860
Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Competition between the RNA tr ...... strong R-loop initiation site.
@en
Competition between the RNA tr ...... strong R-loop initiation site.
@nl
type
label
Competition between the RNA tr ...... strong R-loop initiation site.
@en
Competition between the RNA tr ...... strong R-loop initiation site.
@nl
prefLabel
Competition between the RNA tr ...... strong R-loop initiation site.
@en
Competition between the RNA tr ...... strong R-loop initiation site.
@nl
P2093
P2860
P356
P1476
Competition between the RNA tr ...... strong R-loop initiation site.
@en
P2093
Chih-Lin Hsieh
Deepankar Roy
Michael R Lieber
Zheng Zhang
Zhengfei Lu
P2860
P304
P356
10.1128/MCB.00897-09
P407
P577
2010-01-01T00:00:00Z