Human cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment.
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Differential regulation of sentrinized proteins by a novel sentrin-specific proteaseEvidence for a role of the cellular ND10 protein PML in mediating intrinsic immunity against human cytomegalovirus infectionsDifferential role of Sp100 isoforms in interferon-mediated repression of herpes simplex virus type 1 immediate-early protein expressionHuman cytomegalovirus infection causes degradation of Sp100 proteins that suppress viral gene expressionThe promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoterViral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruptionProteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression.Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivatorAbility of the human cytomegalovirus IE1 protein to modulate sumoylation of PML correlates with its functional activities in transcriptional regulation and infectivity in cultured fibroblast cellsFormation of nuclear foci of the herpes simplex virus type 1 regulatory protein ICP4 at early times of infection: localization, dynamics, recruitment of ICP27, and evidence for the de novo induction of ND10-like complexesCovalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1P-TEFb goes viralThe potential link between PML NBs and ICP0 in regulating lytic and latent infection of HSV-1The Role of Nuclear Antiviral Factors against Invading DNA Viruses: The Immediate Fate of Incoming Viral GenomesRNA polymerase II localizes at sites of human cytomegalovirus immediate-early RNA synthesis and processingCyclin-dependent kinase-like function is shared by the beta- and gamma- subset of the conserved herpesvirus protein kinasesAdenovirus type 5 early region 1B 55K oncoprotein-dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cellsND10 components relocate to sites associated with herpes simplex virus type 1 nucleoprotein complexes during virus infection.Infection of cells with human cytomegalovirus during S phase results in a blockade to immediate-early gene expression that can be overcome by inhibition of the proteasome.Segmentation of fluorescence microscopy images for quantitative analysis of cell nuclear architecture.Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PMLPersistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins.The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoformsElimination of ie1 significantly attenuates murine cytomegalovirus virulence but does not alter replicative capacity in cell cultureThe human cytomegalovirus IE2 and UL112-113 proteins accumulate in viral DNA replication compartments that initiate from the periphery of promyelocytic leukemia protein-associated nuclear bodies (PODs or ND10)The major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth.Origin-independent assembly of Kaposi's sarcoma-associated herpesvirus DNA replication compartments in transient cotransfection assays and association with the ORF-K8 protein and cellular PML.Exon 3 of the human cytomegalovirus major immediate-early region is required for efficient viral gene expression and for cellular cyclin modulation.Interactions of herpes simplex virus type 1 with ND10 and recruitment of PML to replication compartments.Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9Accumulation and intranuclear distribution of unintegrated human immunodeficiency virus type 1 DNA.Functional interaction of nuclear domain 10 and its components with cytomegalovirus after infections: cross-species host cells versus native cells.Regulation of the subcellular distribution of key cellular RNA-processing factors during permissive human cytomegalovirus infectionPrespliceosomal assembly on microinjected precursor mRNA takes place in nuclear specklesRole of noncovalent SUMO binding by the human cytomegalovirus IE2 transactivator in lytic growth.Selective association of peroxiredoxin 1 with genomic DNA and COX-2 upstream promoter elements in estrogen receptor negative breast cancer cells.Cellular proteins localized at and interacting within ND10/PML nuclear bodies/PODs suggest functions of a nuclear depot.Human cytomegalovirus infection induces specific hyperphosphorylation of the carboxyl-terminal domain of the large subunit of RNA polymerase II that is associated with changes in the abundance, activity, and localization of cdk9 and cdk7.Functional interaction between the pp71 protein of human cytomegalovirus and the PML-interacting protein human Daxx.
P2860
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P2860
Human cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Human cytomegalovirus immediat ...... ediate transcript environment.
@ast
Human cytomegalovirus immediat ...... ediate transcript environment.
@en
type
label
Human cytomegalovirus immediat ...... ediate transcript environment.
@ast
Human cytomegalovirus immediat ...... ediate transcript environment.
@en
prefLabel
Human cytomegalovirus immediat ...... ediate transcript environment.
@ast
Human cytomegalovirus immediat ...... ediate transcript environment.
@en
P2093
P2860
P356
P1476
Human cytomegalovirus immediat ...... ediate transcript environment.
@en
P2093
P2860
P356
10.1083/JCB.138.1.5
P407
P577
1997-07-01T00:00:00Z