Functional analysis of the transcription repressor PLU-1/JARID1B. - Wikidata - wikimedia - TriplyDB

Functional analysis of the transcription repressor PLU-1/JARID1B.

Functional analysis of the transcription repressor PLU-1/JARID1B.

http://www.wikidata.org/entity/Q36315263

about

JARID1B is a luminal lineage-driving oncogene in breast cancer Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif Histone demethylase lysine demethylase 5B in development and cancer Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2 Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes JARID1B Expression Plays a Critical Role in Chemoresistance and Stem Cell-Like Phenotype of Neuroblastoma Cells The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3.The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation Genomic profiling of type-1 adult diabetic and aged normoglycemic mouse liver.Essential functions of the histone demethylase lid Time-series clustering of gene expression in irradiated and bystander fibroblasts: an application of FBPA clustering.The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence.The ZNF217 oncogene is a candidate organizer of repressive histone modifiers.Chromatin and oxygen sensing in the context of JmjC histone demethylases Jumonji/ARID1 B (JARID1B) protein promotes breast tumor cell cycle progression through epigenetic repression of microRNA let-7e.Coordinated methyl-lysine erasure: structural and functional linkage of a Jumonji demethylase domain and a reader domain.FOXP3 orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by recruiting MOF and causing displacement of PLU-1.Jarid1b targets genes regulating development and is involved in neural differentiation Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development.JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells.Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders.Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448 Emerging themes from EBV and KSHV microRNA targets Histone demethylases and cancer.Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds Pthlh, a promising cancer modifier gene in rat tongue carcinogenesis Recent advances in the ARID family: focusing on roles in human cancer.The role of maintenance proteins in the preservation of epithelial cell identity during mammary gland remodeling and breast cancer initiation.Epigenetic aberrations during oncogenesis.Chromatin dynamics: H3K4 methylation and H3 variant replacement during development and in cancer.Melanoma epigenetics: novel mechanisms, markers, and medicines.JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral Cancers JARID1B deletion induced apoptosis in Jeko-1 and HL-60 cell lines.HEXIM1 plays a critical role in the inhibition of the androgen receptor by anti-androgens.The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers.SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase.

P2860

Q24299326-4C92F967-E167-4AA4-82A4-C5E03B59BBFC Q24605342-37C36F92-28C9-452F-BFF0-78B532653D9D Q27649841-F79EC9A1-61F7-4AA6-8FE6-48D9DDE42DFD Q28076257-10A9492A-BA75-48EE-990A-AB7B897DFC13 Q28280326-57E37604-07AE-44D9-B443-F33AB19A06BB Q28511595-F42AC99F-7D5B-43BC-8087-E1AD0BFD4B25 Q28547102-CAE7B59F-D3DF-4864-8620-1326DB0B4292 Q30391612-A56655A4-77DD-4E00-835E-DE7576BDA1A0 Q33557525-78811C99-891F-4C1F-B864-350BC05473F9 Q33592783-B87E6456-CC88-45D4-B582-72BA5674E767 Q33760830-473B028A-E0BD-4646-AD3B-2391770EA82B Q33785409-F2D041D3-4198-4D3C-A52B-CBB18585A6E1 Q34042999-98571395-7DF9-42A0-AC51-79590F52C1CF Q34090323-AFFABE1A-CC01-4BAE-ABE7-763CD0415DAE Q34103385-846E95B5-4CB5-4DCC-B5D3-A73C6D67D10D Q35562595-C83A7249-FDC1-4DF6-AF79-2F7732C7AC26 Q35596988-391B3BE8-602B-4853-BC8E-830D85946274 Q35624706-E62D4E21-29F7-4818-9B19-65030A55EC8E Q35626323-0E65A0F1-4750-486D-95FB-703AB0818BE3 Q35779296-E87EF7B3-23E5-47BC-9309-710623B52902 Q35828666-942AC616-FDAD-471B-A39F-E5A8AFB10E27 Q35849485-02FD7724-D7CC-4E21-A038-6F52D0684457 Q35936553-214CAE71-5CC6-4D4A-B509-5BB97244B012 Q36404184-8306B9D1-F7FD-4B19-9464-A6D34B2CD3C4 Q36421138-46E039EA-2A5B-432D-8007-9D4192789A12 Q36548335-1F02F08B-FA2B-4900-ADFE-5258B6E24CA5 Q36725098-7C827EF0-8A7E-4ACA-8BEC-287E3BEC3A0D Q36973683-56909EBD-B81C-4EDD-A453-4F2626DA7B92 Q37120958-DEE96486-80A7-4A78-B7A8-91E4C35903EF Q37404551-B373B503-275A-46E5-8310-7334E2F30486 Q37601383-3D9F0765-E2BF-41B4-9D23-A1E127F3ED93 Q37603631-1408FC70-F019-4CFE-9CC5-ED6D747A7EC6 Q37830385-0E48A922-9DBE-499C-969D-02B7CDA5953A Q38199995-69BB150D-009F-4C36-A66C-E2D48CA19ED4 Q38224624-F93D0CB6-6DA2-4C76-8FA6-517AE11AE7D5 Q38753975-F2F24E3A-F5A8-4694-9CF5-AA18BEC6F1B4 Q38901731-AA706E10-051A-41B1-BCB7-9CE352811B51 Q38993411-C22A300D-95AB-48E4-A0EF-7AD906C45C03 Q39035516-14771E00-21FB-4B22-B3C2-EF93A9123B59 Q39106335-B84874A1-B1CE-4913-A3FA-DE81679137C2

P2860

Functional analysis of the transcription repressor PLU-1/JARID1B.

http://www.wikidata.org/entity/Q36315263

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh

2007年學術文章

@zh-hant

name

Functional analysis of the transcription repressor PLU-1/JARID1B.

@ast

Functional analysis of the transcription repressor PLU-1/JARID1B.

@en

type

label

Functional analysis of the transcription repressor PLU-1/JARID1B.

@ast

Functional analysis of the transcription repressor PLU-1/JARID1B.

@en

prefLabel

Functional analysis of the transcription repressor PLU-1/JARID1B.

@ast

Functional analysis of the transcription repressor PLU-1/JARID1B.

@en

P1433

Q36315263-7A0CCAE9-FEC4-4EED-8AD9-03A4C6280BBA

P1476

Q36315263-6F4352F8-43EA-4AB7-8516-69E2B69B67D0

P2093

Q36315263-0B886F58-C0E1-40FD-827C-7E388E2ECE25

Q36315263-14BF6357-FDA0-4B6C-B55C-89E1E3BC5EFF

Q36315263-2F824573-F5D1-4067-A4D4-45B3E45F5861

Q36315263-70C1AADD-09E0-4363-8F99-AD5144F8F12F

Q36315263-9EA4C762-A602-4D37-AD10-E5001476E3EA

Q36315263-A91285E0-D09F-4932-9C05-452439569861

Q36315263-ED93B3ED-76A7-4754-B4A1-7BB71008C117

Q36315263-F9499C43-D43B-4988-9102-92E1F924DFD7

P2860

Q36315263-03061327-3584-4F6D-90FF-2ECA5AF1BBAB

Q36315263-1ABC679D-2296-4407-8C65-018217D65C11

Q36315263-1B29262F-4015-4010-974C-95389691BC28

Q36315263-1D758DC4-1CED-4843-A1E3-C82F811E5E46

Q36315263-1EF56EC2-0D0D-438D-BFBD-8D412AA18388

Q36315263-20726420-A9F1-44FA-9FEF-5368E348E0C4

Q36315263-26EB6634-C7AB-4BF2-B8BD-FDC74CDA875C

Q36315263-27728CCA-8F24-4257-89C7-2EF2FD1779B7

Q36315263-28D5921F-C530-4E5C-9DC2-8CF24D5B142F

Q36315263-2A7E2D63-B804-4861-8772-EFB324196A2B

P304

Q36315263-C0BA11D3-0A11-4360-88C8-5FFE4FEF23A6

P31

Q36315263-931DAADE-3C99-47EB-8A9D-EFB7A23472E2

P356

Q36315263-E4D81DC1-36D5-4A67-BA71-39DD8DC67108

P407

Q36315263-04ABE6DB-B1F7-4069-B681-9E682425C00D

P433

Q36315263-7718856B-263D-4355-8D1C-2A363985EBDD

P478

Q36315263-B3A92EEE-05E6-48F0-A750-7886188CE8B1

P50

Q36315263-2A222619-2D15-4A0B-B6D0-1E8AE63F24E7

P577

Q36315263-CF73489D-8F47-4CC0-A120-64899D9B2FA5

P698

Q36315263-00C1B304-A792-4865-A737-FD7ABDE744FA

P932

Q36315263-9BFD4326-B089-4F72-9C0A-2939B04EA9A0

P356

P1433

Molecular and Cellular Biology

P1476

Functional analysis of the transcription repressor PLU-1/JARID1B

@en

P2093

Angelo G Scibetta

http://www.w3.org/2001/XMLSchema#string

Debbie Hall

http://www.w3.org/2001/XMLSchema#string

John Copier

http://www.w3.org/2001/XMLSchema#string

Joyce Taylor-Papadimitriou

http://www.w3.org/2001/XMLSchema#string

Julia Coleman

http://www.w3.org/2001/XMLSchema#string

Samantha Santangelo

http://www.w3.org/2001/XMLSchema#string

Steve Catchpole

http://www.w3.org/2001/XMLSchema#string

Tracy Chaplin

http://www.w3.org/2001/XMLSchema#string

P2860

The novel Mrf-2 DNA-binding domain recognizes a five-base core sequence through major and minor-groove contacts

A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer

Regulation of chromatin structure by site-specific histone H3 methyltransferases

Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated transcription

Cell cycle-dependent expression and nucleolar localization of hCAP-H

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9

The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

P304

7220-7235

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/MCB.00274-07

http://www.w3.org/2001/XMLSchema#string

P407

P433

20

http://www.w3.org/2001/XMLSchema#string

P478

27

http://www.w3.org/2001/XMLSchema#string

P50

P577

2007-08-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

17709396

http://www.w3.org/2001/XMLSchema#string

P932

2168894

http://www.w3.org/2001/XMLSchema#string