Targeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases. - Wikidata - wikimedia - TriplyDB

Targeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases.

Targeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases.

http://www.wikidata.org/entity/Q36330960

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Neuroprotective effects of physical activity on the brain: a closer look at trophic factor signaling Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity M1 and M2 immune activation in Parkinson's Disease: Foe and ally?Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis Thioredoxin-Mimetic-Peptides Protect Cognitive Function after Mild Traumatic Brain Injury (mTBI)Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms A synopsis on the role of tyrosine hydroxylase in Parkinson's disease Growth factors in synaptic function.Tumor necrosis factor-α synthesis inhibitor, 3,6'-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice Citric acid effects on brain and liver oxidative stress in lipopolysaccharide-treated mice.Puerarin prevents tumor necrosis factor-α-induced apoptosis of PC12 cells via activation of the PI3K/Akt signaling pathway.Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence Subtype and regional-specific neuroinflammation in sporadic creutzfeldt-jakob disease.Intracerebroventricular injection of encapsulated human mesenchymal cells producing glucagon-like peptide 1 prolongs survival in a mouse model of ALS.Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury Long-term treatment of thalidomide ameliorates amyloid-like pathology through inhibition of β-secretase in a mouse model of Alzheimer's disease.Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model.Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation.Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease Quercetin and sesamin protect dopaminergic cells from MPP+-induced neuroinflammation in a microglial (N9)-neuronal (PC12) coculture system.Involvement of Mu Opioid Receptor Signaling in the Protective Effect of Opioid against 6-Hydroxydopamine-Induced SH-SY5Y Human Neuroblastoma Cells Apoptosis.Blast traumatic brain injury-induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4.Molecular interaction study of N1-p-fluorobenzyl-cymserine with TNF-α , p38 kinase and JNK kinase.Exploring N(1)-p-fluorobenzyl-cymserine as an inhibitor of 5-lipoxygenase as a candidate for type 2 diabetes and neurodegenerative disorder treatment.Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat.Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice Alzheimer's disease and type 2 diabetes: exploring the association to obesity and tyrosine hydroxylase Glucose-Dependent Insulinotropic Polypeptide Ameliorates Mild Traumatic Brain Injury-Induced Cognitive and Sensorimotor Deficits and Neuroinflammation in Rats.Design, synthesis and biological assessment of novel N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines and 3-substituted 2,6-dioxopiperidines for TNF-α inhibitory activity.Neuroinflammation in animal models of traumatic brain injury.Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy Neuroinflammation in Alzheimer's disease: an understanding of physiology and pathology.Linking Alzheimer's disease and type 2 diabetes mellitus via aberrant insulin signaling and inflammation.Association of glycogen synthase kinase-3β with Parkinson's disease (review).Lifestyle Modulators of Neuroplasticity: How Physical Activity, Mental Engagement, and Diet Promote Cognitive Health during Aging.Perispinal Delivery of CNS Drugs.

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Targeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases.

http://www.wikidata.org/entity/Q36330960

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CNS and Neurological Disorders

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David Tweedie

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Kathryn A Frankola

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Nigel H Greig

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Weiming Luo

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P2860

Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer's disease.

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?

Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease

Thalidomide is an inhibitor of angiogenesis

Thalidomide analogues as anticancer drugs

TNF-alpha modulation for treatment of Alzheimer's disease: a 6-month pilot study

Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice

Does neuroinflammation fan the flame in neurodegenerative diseases?

Alzheimer's disease: genes, proteins, and therapy

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3

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neurodegeneration

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