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The effect of ABCB1 polymorphisms on the outcome of breast cancer treatmentSmall and Innovative Molecules as New Strategy to Revert MDRStructures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound statesExhaustive sampling of docking poses reveals binding hypotheses for propafenone type inhibitors of P-glycoprotein.Probing the conformation of the resting state of a bacterial multidrug ABC transporter, BmrA, by a site-directed spin labeling approachCharacterization of an asymmetric occluded state of P-glycoprotein with two bound nucleotides: implications for catalysisABC multidrug transporters: structure, function and role in chemoresistance.Structural characterization of two metastable ATP-bound states of P-glycoprotein.Conformational analysis of human ATP-binding cassette transporter ABCB1 in lipid nanodiscs and inhibition by the antibodies MRK16 and UIC2.Role of ATP binding and hydrolysis in the gating of the cystic fibrosis transmembrane conductance regulatorNew insight into the biochemical mechanisms regulating auxin transport in plants.Drug resistance in cancer - searching for mechanisms, markers and therapeutic agents.Modeling kinetics of subcellular disposition of chemicals.Overcoming drug resistance in patients with metastatic breast cancer.Multidrug efflux pumps: drug binding--gates or cavity?The P-glycoprotein multidrug transporter.Prenylated caged xanthones: chemistry and biology.Pregnane X Receptor and P-glycoprotein: a connexion for Alzheimer's disease management.Reaction dynamics of ATP hydrolysis catalyzed by P-glycoprotein.Advances in plant-based inhibitors of P-glycoprotein.Reversal effect of ouabain on multidrug resistance in esophageal carcinoma EC109/CDDP cells by inhibiting the translocation of Wnt/β-catenin into the nucleus.Synergistic effect of hyperthermia and neferine on reverse multidrug resistance in adriamycin-resistant SGC7901/ADM gastric cancer cells.Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2?Cellular pharmacology and potency of HIV-1 nucleoside analogs in primary human macrophages.Structural insights into P-glycoprotein (ABCB1) by small angle X-ray scattering and electron crystallography.The Walker B motif of the second nucleotide-binding domain (NBD2) of CFTR plays a key role in ATPase activity by the NBD1-NBD2 heterodimer.Transmembrane helix 12 modulates progression of the ATP catalytic cycle in ABCB1.Determining P-glycoprotein-drug interactions: evaluation of reconstituted P-glycoprotein in a liposomal system and LLC-MDR1 polarized cell monolayers.Shedding light on drug transport: structure and function of the P-glycoprotein multidrug transporter (ABCB1).
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The translocation mechanism of P-glycoprotein.
@ast
The translocation mechanism of P-glycoprotein.
@en
type
label
The translocation mechanism of P-glycoprotein.
@ast
The translocation mechanism of P-glycoprotein.
@en
prefLabel
The translocation mechanism of P-glycoprotein.
@ast
The translocation mechanism of P-glycoprotein.
@en
P2093
P2860
P50
P1433
P1476
The translocation mechanism of P-glycoprotein
@en
P2093
Ian D Kerr
Richard Callaghan
Robert C Ford
P2860
P304
P356
10.1016/J.FEBSLET.2005.11.083
P407
P577
2005-12-19T00:00:00Z