Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function
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Notch1 augments NF-kappaB activity by facilitating its nuclear retentionTo be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosisActivation of PI3-kinase/PKB contributes to delay in neutrophil apoptosis after thermal injuryABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responsesTargeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival.Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery.c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells.Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome.The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation.Roles of the NF-kappaB pathway in lymphocyte development and function.Premalignant PTEN-deficient thymocytes activate microRNAs miR-146a and miR-146b as a cellular defense against malignant transformation.Cell-intrinsic NF-κB activation is critical for the development of natural regulatory T cells in mice.Sitagliptin (MK0431) inhibition of dipeptidyl peptidase IV decreases nonobese diabetic mouse CD4+ T-cell migration through incretin-dependent and -independent pathways.Tissue specific deletion of inhibitor of kappa B kinase 2 with OX40-Cre reveals the unanticipated expression from the OX40 locus in skin epidermis.NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2Transcriptional control of invariant NKT cell development.Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development.IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival.Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.NF-kappaB regulation of endothelial cell function during LPS-induced toxemia and cancer.Spaceflight and simulated microgravity cause a significant reduction of key gene expression in early T-cell activationThe c-Rel Transcription Factor in Development and Disease.The NF-κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory propertiesCARMA1 controls Th2 cell-specific cytokine expression through regulating JunB and GATA3 transcription factors.Chronic activation of the kinase IKKβ impairs T cell function and survival.Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.The Rel/NF-κB pathway and transcription of immediate early genes in T cell activation are inhibited by microgravity.NF-kappaB guides the survival and differentiation of developing lymphocytes.The pro-apoptotic effects of TIPE2 on AA rat fibroblast-like synoviocytes via regulation of the DR5-caspase-NF-κB pathway in vitro.NF-kappa B as a therapeutic target in autoimmune disease.The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis.Dissection of TBK1 signaling via phosphoproteomics in lung cancer cellsCrosstalk via the NF-kappaB signaling system.A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activationControl of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse.Differential requirement for CARMA1 in agonist-selected T-cell development.PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice.MicroRNA-21 regulates T-cell apoptosis by directly targeting the tumor suppressor gene Tipe2.CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters.Doxycycline is an NF-κB inhibitor that induces apoptotic cell death in malignant T-cells.
P2860
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P2860
Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Combined deficiency of p50 and ...... survival and in vivo function
@ast
Combined deficiency of p50 and ...... survival and in vivo function
@en
type
label
Combined deficiency of p50 and ...... survival and in vivo function
@ast
Combined deficiency of p50 and ...... survival and in vivo function
@en
prefLabel
Combined deficiency of p50 and ...... survival and in vivo function
@ast
Combined deficiency of p50 and ...... survival and in vivo function
@en
P2093
P2860
P356
P1476
Combined deficiency of p50 and ...... survival and in vivo function
@en
P2093
Amer A Beg
Jesse Lyons
Luk Van Parijs
Monika Vig
P2860
P304
P356
10.1084/JEM.20021610
P407
P577
2003-03-31T00:00:00Z