Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers
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Interferon-gamma and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cellsDegeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humansTCR Signaling in T Cell MemoryLower Affinity T Cells are Critical Components and Active Participants of the Immune ResponseTargeting Epigenetic Processes in Photodynamic Therapy-Induced Anticancer ImmunityThe multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cellsMore tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimersStructural Comparison of Allogeneic and Syngeneic T Cell Receptor–Peptide-Major Histocompatibility Complex ComplexesThe Crystal Structure of CD8 in Complex with YTS156.7.7 Fab and Interaction with Other CD8 Antibodies Define the Binding Mode of CD8 αβ to MHC Class IDistinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientationDifferent Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors † ‡CD3 delta establishes a functional link between the T cell receptor and CD8Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infectionInterplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagementTwo-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discriminationPeptide vaccination in Montanide adjuvant induces and GM-CSF increases CXCR3 and cutaneous lymphocyte antigen expression by tumor antigen-specific CD8 T cells.Redirecting human CD4+ T lymphocytes to the MHC class I-restricted melanoma antigen MAGE-A1 by TCR alphabeta gene transfer requires CD8alpha.Engineering higher affinity T cell receptors using a T cell display system.In situ detection of Gag-specific CD8+ cells in the GI tract of SIV infected Rhesus macaques.The impact of TCR-binding properties and antigen presentation format on T cell responsiveness.Nonspecific down-regulation of CD8+ T-cell responses in mice expressing human papillomavirus type 16 E7 oncoprotein from the keratin-14 promoter.Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells.Contribution of T cell receptor affinity to overall avidity for virus-specific CD8+ T cell responsesDifferences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor.Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors.Soluble peptide-MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules.Class I negative CD8 T cells reveal the confounding role of peptide-transfer onto CD8 T cells stimulated with soluble H2-Kb molecules.The T cell receptor for antigen: signaling and ligand discrimination.Design of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responses.IL-2 complex treatment can protect naive mice from bacterial and viral infection.The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens.Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRsA role for CD8 in the developmental tuning of antigen recognition and CD3 conformational change.Memory generation and maintenance of CD8+ T cell function during viral persistenceAn evolutionary and structural perspective on T cell antigen receptor function.Direct targeted glycation of the free sulfhydryl group of cysteine residue (Cys-34) of BSA. Mapping of the glycation sites of the anti-tumor Thomsen-Friedenreich neoglycoconjugate vaccine prepared by Michael addition reaction.Intravascular staining for discrimination of vascular and tissue leukocytes.Stage-dependent reactivity of thymocytes to self-peptide--MHC complexes.CD8 co-receptor promotes susceptibility of CD8+ T cells to transforming growth factor-β (TGF-β)-mediated suppression.Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation
P2860
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P2860
Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers
description
2000 nî lūn-bûn
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2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
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2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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name
Critical role for CD8 in T cel ...... ompatibility complex multimers
@ast
Critical role for CD8 in T cel ...... ompatibility complex multimers
@en
type
label
Critical role for CD8 in T cel ...... ompatibility complex multimers
@ast
Critical role for CD8 in T cel ...... ompatibility complex multimers
@en
prefLabel
Critical role for CD8 in T cel ...... ompatibility complex multimers
@ast
Critical role for CD8 in T cel ...... ompatibility complex multimers
@en
P2860
P356
P1476
Critical role for CD8 in T cel ...... ompatibility complex multimers
@en
P2093
M A Daniels
S C Jameson
P2860
P304
P356
10.1084/JEM.191.2.335
P407
P577
2000-01-01T00:00:00Z