Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion.
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Exposure to asphalt fumes activates activator protein-1 through the phosphatidylinositol 3-Kinase/Akt signaling pathway in mouse epidermal cellsCyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activityInduction of activator protein-1 through reactive oxygen species by crystalline silica in JB6 cellsMetallic nickel nanoparticles may exhibit higher carcinogenic potential than fine particles in JB6 cellsInhibition of AP-1 and neoplastic transformation by fresh apple peel extractAC3-33, a novel secretory protein, inhibits Elk1 transcriptional activity via ERK pathwayThe promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damageKaposi's sarcoma-associated herpesvirus induction of AP-1 and interleukin 6 during primary infection mediated by multiple mitogen-activated protein kinase pathways.Retinoic acid receptors inhibit AP1 activation by regulating extracellular signal-regulated kinase and CBP recruitment to an AP1-responsive promoter.JDP2, a repressor of AP-1, recruits a histone deacetylase 3 complex to inhibit the retinoic acid-induced differentiation of F9 cellsc-JUN prevents methylation of p16(INK4a) (and Cdk6): the villain turned bodyguardSuppressor role of activating transcription factor 2 (ATF2) in skin cancerAP-1, NF-kappa-B, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model.Cancer prevention with promising natural products: mechanisms of action and molecular targetsStructural and functional analysis of the natural JNK1 inhibitor quercetagetinOncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylationA novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivationThe AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in miceThe growth of malignant keratinocytes depends on signaling through the PGE(2) receptor EP1Activation of p38 MAP kinase and JNK pathways by UVA irradiationOxidants and signaling by mitogen-activated protein kinases in lung epitheliumThe transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translationEffect of deoxyribozymes targeting c-Jun on solid tumor growth and angiogenesis in rodentsSuppression of AP1 transcription factor function in keratinocyte suppresses differentiationAP-1 in cell proliferation and survivalAP-1 differentially expressed proteins Krp1 and fibronectin cooperatively enhance Rho-ROCK-independent mesenchymal invasion by altering the function, localization, and activity of nondifferentially expressed proteins.Small molecule inhibitors targeting activator protein 1 (AP-1).Regulation of a multigenic invasion programme by the transcription factor, AP-1: re-expression of a down-regulated gene, TSC-36, inhibits invasion.Heparin (GAG-hed) inhibits LCR activity of human papillomavirus type 18 by decreasing AP1 binding.A high-throughput cell-based assay to identify specific inhibitors of transcription factor AP-1.Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activitiesInhibitory effects of Baicalin on ultraviolet B-induced photo-damage in keratinocyte cell line.A selective small-molecule nuclear factor-kappaB inhibitor from a high-throughput cell-based assay for "activator protein-1 hits".Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells.Differentiation-associated genes regulated by c-Jun and decreased in the progression of esophageal squamous cell carcinoma.The anticancer effects of actinoporin RTX-A from the sea anemone Heteractis crispa (=Radianthus macrodactylus)Delphinidin attenuates neoplastic transformation in JB6 Cl41 mouse epidermal cells by blocking Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling.Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition.STAT2 contributes to promotion of colorectal and skin carcinogenesis.Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo.
P2860
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P2860
Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Transgenic mice demonstrate AP ...... required for tumor promotion.
@ast
Transgenic mice demonstrate AP ...... required for tumor promotion.
@en
type
label
Transgenic mice demonstrate AP ...... required for tumor promotion.
@ast
Transgenic mice demonstrate AP ...... required for tumor promotion.
@en
prefLabel
Transgenic mice demonstrate AP ...... required for tumor promotion.
@ast
Transgenic mice demonstrate AP ...... required for tumor promotion.
@en
P2093
P2860
P356
P1476
Transgenic mice demonstrate AP ...... required for tumor promotion.
@en
P2093
B K Sathyanarayana
R A Flavell
R Hunziker
P2860
P304
P356
10.1073/PNAS.96.17.9827
P407
P577
1999-08-01T00:00:00Z