The number of p16INK4a positive cells in human skin reflects biological age. - Wikidata - wikimedia - TriplyDB

The number of p16INK4a positive cells in human skin reflects biological age.

The number of p16INK4a positive cells in human skin reflects biological age.

http://www.wikidata.org/entity/Q36517006

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The secreted protein S100A7 (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulators "Inflammaging" as a Druggable Target: A Senescence-Associated Secretory Phenotype-Centered View of Type 2 Diabetes Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules Cellular Senescence and the Biology of Aging, Disease, and Frailty DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging Defining the toxicology of aging Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.The molecular balancing act of p16(INK4a) in cancer and aging.Aging, cellular senescence, and cancer Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.Clinical strategies and animal models for developing senolytic agents.Senotherapy: growing old and staying young?Resveratrol prevents oxidative stress-induced senescence and proliferative dysfunction by activating the AMPK-FOXO3 cascade in cultured primary human keratinocytes.Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin.Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.The intrinsic stiffness of human trabecular meshwork cells increases with senescence.Absence of AMPKα2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts.Anti-TNF-α treatment modulates SASP and SASP-related microRNAs in endothelial cells and in circulating angiogenic cells.Werner syndrome through the lens of tissue and tumour genomics.Wnt signaling potentiates nevogenesis Identification of Senescent Cells in the Bone Microenvironment.Cellular senescence in osteoarthritis pathology.Cell senescence: role in aging and age-related diseases.Analysis of individual cells identifies cell-to-cell variability following induction of cellular senescence.The Chromatin Landscape of Cellular Senescence.Biomarkers of skin aging.Energetic interventions for healthspan and resiliency with aging.The Clinical Potential of Senolytic Drugs.The Role of p16INK4a Pathway in Human Epidermal Stem Cell Self-Renewal, Aging and Cancer The role of cellular senescence in the gastrointestinal mucosa.P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age.Death by transposition - the enemy within?p16INK4A influences the aging phenotype in the living skin equivalent.Age and aging in blood disorders: multiple myeloma.Selenium preserves keratinocyte stemness and delays senescence by maintaining epidermal adhesion.Cellular senescence occurred widespread to multiple selective sites in the fetal tissues and organs of mice.MicroRNA-663 induction upon oxidative stress in cultured human fibroblasts depends on the chronological age of the donor.Do senescence markers correlate in vitro and in situ within individual human donors?Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

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P2860

The number of p16INK4a positive cells in human skin reflects biological age.

http://www.wikidata.org/entity/Q36517006

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2012 nî lūn-bûn

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2012年论文

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2012年论文

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name

The number of p16INK4a positive cells in human skin reflects biological age.

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The number of p16INK4a positive cells in human skin reflects biological age.

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The number of p16INK4a positive cells in human skin reflects biological age.

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The number of p16INK4a positive cells in human skin reflects biological age.

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The number of p16INK4a positive cells in human skin reflects biological age.

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The number of p16INK4a positive cells in human skin reflects biological age.

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J.1474-9726.2012.00837.X

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The number of p16INK4a positive cells in human skin reflects biological age.

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Anton J M de Craen

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Barbara H Strongitharm

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David A Gunn

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Diana van Heemst

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John M Sedivy

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Mariëtte E C Waaijer

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Rudi G J Westendorp

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William E Parish

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P2860

Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

p16INK4a induces an age-dependent decline in islet regenerative potential

Ink4a/Arf expression is a biomarker of aging

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

Cellular senescence: when bad things happen to good cells

Cellular senescence in pretransplant renal biopsies predicts postoperative organ function.

Does oxidative damage to DNA increase with age?

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4

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Pieternella E Slagboom

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225051863

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