Nonracemic Antifolates Stereoselectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus.
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Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosisEndless Resistance. Endless Antibiotics?Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates.Antibacterial Antifolates: From Development through Resistance to the Next GenerationMRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens.Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations.Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse.Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks.Characterization of trimethoprim resistant E. coli dihydrofolate reductase mutants by mass spectrometry and inhibition by propargyl-linked antifolates.
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P2860
Nonracemic Antifolates Stereoselectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
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2015年论文
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2015年论文
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name
Nonracemic Antifolates Stereos ...... rcome Resistance in S. aureus.
@ast
Nonracemic Antifolates Stereos ...... rcome Resistance in S. aureus.
@en
type
label
Nonracemic Antifolates Stereos ...... rcome Resistance in S. aureus.
@ast
Nonracemic Antifolates Stereos ...... rcome Resistance in S. aureus.
@en
prefLabel
Nonracemic Antifolates Stereos ...... rcome Resistance in S. aureus.
@ast
Nonracemic Antifolates Stereos ...... rcome Resistance in S. aureus.
@en
P2860
P356
P1476
Nonracemic Antifolates Stereos ...... rcome Resistance in S. aureus.
@en
P2093
Amy C Anderson
Santosh Keshipeddy
P2860
P304
P356
10.1021/JACS.5B01442
P407
P577
2015-07-08T00:00:00Z