Posttranslational processing of the prohormone-cleaving Kex2 protease in the Saccharomyces cerevisiae secretory pathway
about
Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 proteaseFormation of AP-3 transport intermediates requires Vps41 function.Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins.Shared functions in vivo of a glycosyl-phosphatidylinositol-linked aspartyl protease, Mkc7, and the proprotein processing protease Kex2 in yeast.SOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals.Btn3 is a negative regulator of Btn2-mediated endosomal protein trafficking and prion curing in yeast.The PBN1 gene of Saccharomyces cerevisiae: an essential gene that is required for the post-translational processing of the protease B precursorPurification and characterization of the yeast glycosylphosphatidylinositol-anchored, monobasic-specific aspartyl protease yapsin 2 (Mkc7p).Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteinsThe integral membrane protein snl1p is genetically linked to yeast nuclear pore complex function.Clathrin-dependent localization of alpha 1,3 mannosyltransferase to the Golgi complex of Saccharomyces cerevisiaeMorphogenesis and dynamics of the yeast Golgi apparatus.Evolution of a subtilisin-like protease gene family in the grass endophytic fungus Epichloƫ festucae.Vps1p, a member of the dynamin GTPase family, is necessary for Golgi membrane protein retention in Saccharomyces cerevisiaeSorting of yeast alpha 1,3 mannosyltransferase is mediated by a lumenal domain interaction, and a transmembrane domain signal that can confer clathrin-dependent Golgi localization to a secreted protein.The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization.The Kex2p proregion is essential for the biosynthesis of an active enzyme and requires a C-terminal basic residue for its function.The role of Myo2, a yeast class V myosin, in vesicular transport.O-Glycosylation of Axl2/Bud10p by Pmt4p is required for its stability, localization, and function in daughter cellsTwo separate signals act independently to localize a yeast late Golgi membrane protein through a combination of retrieval and retentionThe Tlg SNARE complex is required for TGN homotypic fusion.A pathway for cell wall anchorage of Saccharomyces cerevisiae alpha-agglutininCell surface anchorage and ligand-binding domains of the Saccharomyces cerevisiae cell adhesion protein alpha-agglutinin, a member of the immunoglobulin superfamily.Protein O-glycosylation in fungi: diverse structures and multiple functions.KEX2 influences Candida albicans proteinase secretion and hyphal formation.Regulation of PACE propeptide-processing activity: requirement for a post-endoplasmic reticulum compartment and autoproteolytic activation.The effects of clathrin inactivation on localization of Kex2 protease are independent of the TGN localization signal in the cytosolic tail of Kex2p.Lessons from fungal F-box proteinsIsolation and characterization of krp, a dibasic endopeptidase required for cell viability in the fission yeast Schizosaccharomyces pombe.Phylogenomic evolutionary surveys of subtilase superfamily genes in fungi.Assessment of MS/MS search algorithms with parent-protein profiling.Activation of the kexin from Schizosaccharomyces pombe requires internal cleavage of its initially cleaved prosequence.Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole.Processing of protein precursors by a novel family of subtilisin-related mammalian endoproteases.A C-terminal domain conserved in precursor processing proteases is required for intramolecular N-terminal maturation of pro-Kex2 protease.Mammalian paired basic amino acid convertases of prohormones and proproteins.Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis.Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation.Posttranslational processing of carboxypeptidase E, a neuropeptide-processing enzyme, in AtT-20 cells and bovine pituitary secretory granules.
P2860
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P2860
Posttranslational processing of the prohormone-cleaving Kex2 protease in the Saccharomyces cerevisiae secretory pathway
description
1991 nĆ® lÅ«n-bĆ»n
@nan
1991幓ć®č«ę
@ja
1991幓č«ę
@yue
1991幓č«ę
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1991幓č«ę
@zh-hk
1991幓č«ę
@zh-mo
1991幓č«ę
@zh-tw
1991幓č®ŗę
@wuu
1991幓č®ŗę
@zh
1991幓č®ŗę
@zh-cn
name
Posttranslational processing o ...... s cerevisiae secretory pathway
@ast
Posttranslational processing o ...... s cerevisiae secretory pathway
@en
type
label
Posttranslational processing o ...... s cerevisiae secretory pathway
@ast
Posttranslational processing o ...... s cerevisiae secretory pathway
@en
prefLabel
Posttranslational processing o ...... s cerevisiae secretory pathway
@ast
Posttranslational processing o ...... s cerevisiae secretory pathway
@en
P2860
P356
P1476
Posttranslational processing o ...... s cerevisiae secretory pathway
@en
P2093
C A Wilcox
R S Fuller
P2860
P304
P356
10.1083/JCB.115.2.297
P407
P577
1991-10-01T00:00:00Z