Cotranscriptional processes and their influence on genome stability.
about
Genome instability and transcription elongation impairment in human cells depleted of THO/TREXNew insights into repeat instability: role of RNA•DNA hybrids3' end mRNA processing: molecular mechanisms and implications for health and diseaseSR proteins in vertical integration of gene expression from transcription to RNA processing to translationProcessing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right endThe RNA Splicing Response to DNA DamageThe Nrd1–Nab3–Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domainYeast aconitase binds and provides metabolically coupled protection to mitochondrial DNAGenetic instability in budding and fission yeast-sources and mechanismsPLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasisLoss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis.Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in miceProtecting exons from deleterious R-loops: a potential advantage of having intronsHighly conserved regimes of neighbor-base-dependent mutation generated the background primary-structural heterogeneities along vertebrate chromosomes.A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability.R loops stimulate genetic instability of CTG.CAG repeats.The SR protein B52/SRp55 is required for DNA topoisomerase I recruitment to chromatin, mRNA release and transcription shutdown.Nascent RNA transcripts facilitate the formation of G-quadruplexes.Noncanonical compensation of zygotic X transcription in early Drosophila melanogaster development revealed through single-embryo RNA-seq.A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expressionSelection for the G4 DNA motif at the 5' end of human genesMaintaining genome stability in the nervous system.DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal.R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters.The RNA polymerase II CTD coordinates transcription and RNA processing.Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damageRNAi-dependent formation of heterochromatin and its diverse functionsArabidopsis BRCA2 and RAD51 proteins are specifically involved in defense gene transcription during plant immune responses.Rescue from replication stress during mitosis.The Pif1 family in prokaryotes: what are our helicases doing in your bacteria?Divergent transcription is associated with promoters of transcriptional regulators.G4 motifs correlate with promoter-proximal transcriptional pausing in human genes.BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair.The annealing helicase and branch migration activities of Drosophila HARP.Molecular biology. A new twist for topoisomerase.Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin.R-loop-mediated genomic instability is caused by impairment of replication fork progressionDNA methylome and transcriptome sequencing in human ovarian granulosa cells links age-related changes in gene expression to gene body methylation and 3'-end GC density.Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability.Transcription as a source of genome instability.
P2860
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P2860
Cotranscriptional processes and their influence on genome stability.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Cotranscriptional processes and their influence on genome stability.
@ast
Cotranscriptional processes and their influence on genome stability.
@en
type
label
Cotranscriptional processes and their influence on genome stability.
@ast
Cotranscriptional processes and their influence on genome stability.
@en
prefLabel
Cotranscriptional processes and their influence on genome stability.
@ast
Cotranscriptional processes and their influence on genome stability.
@en
P356
P1433
P1476
Cotranscriptional processes and their influence on genome stability
@en
P2093
P304
P356
10.1101/GAD.1438306
P577
2006-07-01T00:00:00Z