MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).
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MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger proteinAF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23)Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear specklesActivation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion proteinMOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2FOXP3 ensembles in T-cell regulationFOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repressionNew insight into the molecular mechanisms of MLL-associated leukemiaMLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein functionMLL and CREB bind cooperatively to the nuclear coactivator CREB-binding proteinLeukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteinst(11;22)(q23;q11.2) In acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromesNuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300/CREB-binding protein (CBP)Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemiaCBP/p300 interact with and function as transcriptional coactivators of BRCA1Epigenetics of cervical cancer. An overview and therapeutic perspectivesProtein lysine acetylation by p300/CBPp53 Acetylation: Regulation and ConsequencesHistone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cellst(10;16)(q22;p13) and MORF-CREBBP fusion is a recurrent event in acute myeloid leukemiaHRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2ABET domain co-regulators in obesity, inflammation and cancerTruncating mutations of hSNF5/INI1 in aggressive paediatric cancerSmall changes huge impact: the role of protein posttranslational modifications in cellular homeostasis and diseaseThe mixed lineage leukemia fusion partner AF9 binds specific isoforms of the BCL-6 corepressorInactivating mutations of acetyltransferase genes in B-cell lymphomaHistone Deacetylase Inhibitor Romidepsin Has Differential Activity in Core Binding Factor Acute Myeloid LeukemiaENL, the MLL fusion partner in t(11;19), binds to the c-Abl interactor protein 1 (ABI1) that is fused to MLL in t(10;11)+.Disordered epigenetic regulation in MLL-related leukemia.Functional interaction between the coactivator Drosophila CREB-binding protein and ASH1, a member of the trithorax group of chromatin modifiersTumor-specific and proliferation-specific gene expression typifies murine transgenic B cell lymphomagenesis.E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia.p300 and CBP: partners for life and death.Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation.A function of CBP as a transcriptional co-activator during Dpp signalling.Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.The monocytic leukemia zinc finger protein MOZ is a histone acetyltransferase.Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis
P2860
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P2860
MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
MLL is fused to CBP, a histone ...... ia with a t(11;16)(q23;p13.3).
@ast
MLL is fused to CBP, a histone ...... ia with a t(11;16)(q23;p13.3).
@en
type
label
MLL is fused to CBP, a histone ...... ia with a t(11;16)(q23;p13.3).
@ast
MLL is fused to CBP, a histone ...... ia with a t(11;16)(q23;p13.3).
@en
prefLabel
MLL is fused to CBP, a histone ...... ia with a t(11;16)(q23;p13.3).
@ast
MLL is fused to CBP, a histone ...... ia with a t(11;16)(q23;p13.3).
@en
P2093
P2860
P356
P1476
MLL is fused to CBP, a histone ...... ia with a t(11;16)(q23;p13.3).
@en
P2093
B Schlegelberger
J D Rowley
N A Doggett
N J Zeleznik-Le
O M Sobulo
P2860
P304
P356
10.1073/PNAS.94.16.8732
P407
P577
1997-08-01T00:00:00Z