TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
about
Protein tyrosine phosphatases as wardens of STAT signalingPancreatic T cell protein-tyrosine phosphatase deficiency ameliorates cerulein-induced acute pancreatitis.Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium.The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling.Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.Constitutive activation of STAT3 in breast cancer cells: A review.Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence.On the role of tyrosine phosphatases as negative regulators of STAT signaling in breast cancers: new findings and future perspectives.Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor developmentUnderstanding the biology of reactive oxygen species and their link to cancer: NADPH oxidases as novel pharmacological targets.Src family kinases and their role in hematological malignancies.Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines.The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis.Loss of protein tyrosine phosphatase, non-receptor type 2 is associated with activation of AKT and tamoxifen resistance in breast cancer.The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals.UVB-induced nuclear translocation of TC-PTP by AKT/14-3-3σ axis inhibits keratinocyte survival and proliferation.Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells.The STAT3 inhibitor pyrimethamine displays anti-cancer and immune stimulatory effects in murine models of breast cancer.Combined drug therapeutic strategies for the effective treatment of Triple Negative Breast Cancer.Predicting and Overcoming Chemotherapeutic Resistance in Breast Cancer.The impact of phosphatases on proliferative and survival signaling in cancer.A new synthetic derivative of cryptotanshinone KYZ3 as STAT3 inhibitor for triple-negative breast cancer therapyThe Role of TCPTP in CancerProtein Tyrosine Phosphatases as Potential Regulators of STAT3 SignalingObesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
P2860
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P2860
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
@ast
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
@en
type
label
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
@ast
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
@en
prefLabel
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
@ast
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
@en
P2093
P2860
P50
P356
P1476
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers
@en
P2093
Benjamin J Shields
Florian Wiede
Hong-Jian Zhu
Kenneth Wee
Robert L Sutherland
Sandra A O'Toole
Timothy J Molloy
P2860
P304
P356
10.1128/MCB.01016-12
P407
P577
2012-11-19T00:00:00Z