Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene
about
The quantal theory of how the immune system discriminates between "self and non-self"CIS associates with the interleukin-2 receptor beta chain and inhibits interleukin-2-dependent signalingStat5b is essential for natural killer cell-mediated proliferation and cytolytic activityGenomic organization and regulation of the human interleukin-18 gene.MER41 repeat sequences contain inducible STAT1 binding sitesA sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dimers: a distinct biochemical difference between STAT5A and STAT5B.Antiapoptotic function of Cdk9 (TAK/P-TEFb) in U937 promonocytic cells.IL-2 and long-term T cell activation induce physical and functional interaction between STAT5 and ETS transcription factors in human T cells.The role of Stat5a and Stat5b in signaling by IL-2 family cytokines.The significance of tetramerization in promoter recruitment by Stat5.Interleukin-2 (IL-2) regulates the accessibility of the IL-2-responsive enhancer in the IL-2 receptor alpha gene to transcription factorsBinding of HMG-I(Y) imparts architectural specificity to a positioned nucleosome on the promoter of the human interleukin-2 receptor alpha gene.Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locusThe basis for TCR-mediated regulation of the IL-2 receptor alpha chain gene: role of widely separated regulatory elements.T lymphocyte activation--an inside overview.Cytokines and immunodeficiency diseases.A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3.Interferon-α inhibits CD4 T cell responses to interleukin-7 and interleukin-2 and selectively interferes with Akt signaling.The interleukin (IL)-2 family cytokines: survival and proliferation signaling pathways in T lymphocytes.Elf-1 contributes to the function of the complex interleukin (IL)-2-responsive enhancer in the mouse IL-2 receptor alpha gene.CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1-induced T-cell acute lymphoblastic leukemia.Control of IL-2Ralpha gene expression: structural changes within the proximal enhancer/core promoter during T-cell development.STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.CD25 expression and outcomes in older patients with acute myelogenous leukemia treated with plerixafor and decitabine.An inducible enhancer required for Il12b promoter activity in an insulated chromatin environment.Myeloid zinc finger (MZF)-like, Kruppel-like and Ets families of transcription factors determine the cell-specific expression of mouse extracellular superoxide dismutase.Induction of the IL-13 receptor alpha2-chain by IL-4 and IL-13 in human keratinocytes: involvement of STAT6, ERK and p38 MAPK pathways.IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line.Interaction of STAT5 dimers on two low affinity binding sites mediates interleukin 2 (IL-2) stimulation of IL-2 receptor alpha gene transcription.Isolation and initial characterization of the BRCA2 promoter.Characterization of the Stat5 protease.The interleukin 2 receptor alpha chain/CD25 promoter is a target for nuclear factor of activated T cells.Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling.Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b.STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus.Smad-dependent cooperative regulation of interleukin 2 receptor alpha chain gene expression by T cell receptor and transforming growth factor-beta.STAT4 is required for interleukin-12-induced chromatin remodeling of the CD25 locus.
P2860
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P2860
Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Elf-1 and Stat5 bind to a crit ...... erleukin-2 receptor alpha gene
@ast
Elf-1 and Stat5 bind to a crit ...... erleukin-2 receptor alpha gene
@en
type
label
Elf-1 and Stat5 bind to a crit ...... erleukin-2 receptor alpha gene
@ast
Elf-1 and Stat5 bind to a crit ...... erleukin-2 receptor alpha gene
@en
prefLabel
Elf-1 and Stat5 bind to a crit ...... erleukin-2 receptor alpha gene
@ast
Elf-1 and Stat5 bind to a crit ...... erleukin-2 receptor alpha gene
@en
P2093
P2860
P356
P1476
Elf-1 and Stat5 bind to a crit ...... erleukin-2 receptor alpha gene
@en
P2093
Beadling C
P2860
P304
P356
10.1128/MCB.16.12.6829
P407
P577
1996-12-01T00:00:00Z