Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
about
Biology of IL-21 and the IL-21 receptorThe Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell developmentSignaling by STATsJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Targeting NK Cells for Anticancer Immunotherapy: Clinical and Preclinical ApproachesIL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer CellsNucleic acid-based approaches to STAT inhibitionCytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulationImpairment of natural killer cytotoxic activity and interferon gamma production in CCAAT/enhancer binding protein gamma-deficient miceDNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sitesCTLA-4 interacts with STAT5 and inhibits STAT5-mediated transcription.Physical and functional interactions between STAP-2/BKS and STAT5.New insights into the regulation of T cells by gamma(c) family cytokinesSTAT5 activation is critical for the transformation mediated by myeloproliferative disorder-associated JAK2 V617F mutantTherapeutic modulators of STAT signalling for human diseasesRegulation of intestinal barrier function by signal transducer and activator of transcription 5b.STAT5 signaling in sexually dimorphic gene expression and growth patternsJanus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice.IL-2 and long-term T cell activation induce physical and functional interaction between STAT5 and ETS transcription factors in human T cells.The role of Stat5a and Stat5b in signaling by IL-2 family cytokines.The significance of tetramerization in promoter recruitment by Stat5.Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic miceInterleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells.Signaling via the IL-2 and IL-7 receptors from the membrane to the nucleus.Stat5a/b are essential for normal lymphoid development and differentiation.The different functions of Stat5 and chromatin alteration through Stat5 proteinsSTAT5 is critical to maintain effector CD8+ T cell responses.Translocations of the RARalpha gene in acute promyelocytic leukemia.Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signalingOntogeny and expansion of human natural killer cells: clinical implications.Cytokines and immunodeficiency diseases.Molecular mechanisms influencing NK cell development: implications for NK cell malignancies.Inhibition of tumor growth by NK1.1+ cells and CD8+ T cells activated by IL-15 through receptor beta/common gamma signaling in trans.PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsivenessThe role of signal transducers and activators of transcription in T inflammatory bowel diseases.Nonredundant roles for Stat5a/b in directly regulating Foxp3The molecular basis of IL-21-mediated proliferation.Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages.Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways.NK Cell Proliferation Induced by IL-15 Transpresentation Is Negatively Regulated by Inhibitory Receptors.
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P2860
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
description
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Dezember 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/12/07)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/12/07)
@nl
наукова стаття, опублікована в грудні 1998
@uk
مقالة علمية (نشرت في 7-12-1998)
@ar
name
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
@ast
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
@en
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
@nl
type
label
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
@ast
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
@en
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
@nl
prefLabel
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
@ast
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
@en
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
@nl
P2093
P2860
P921
P3181
P356
P1476
Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity
@en
P2093
H Nakajima
J A Horvath-Arcidiacono
W J Leonard
P2860
P304
P3181
P356
10.1084/JEM.188.11.2067
P407
P50
P577
1998-12-01T00:00:00Z