Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.
about
Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humansDissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosine-based inhibitory motifsThe major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signalingInteraction of the tyrosine phosphatase SHP-2 with Gab2 regulates Rho-dependent activation of the c-fos serum response element by interleukin-2Inhibition of topoisomerase I cleavage activity by thiol-reactive compounds: importance of vicinal cysteines 504 and 505Adapter function of protein-tyrosine phosphatase 1D in insulin receptor/insulin receptor substrate-1 interactionProtein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signalingRoles of the complex formation of SHPS-1 with SHP-2 in insulin-stimulated mitogen-activated protein kinase activationActivation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain moleculeKinase activation through dimerization by human SH2-BAssociation of protein-tyrosine phosphatase PTP-BAS with the transcription-factor-inhibitory protein IkappaBalpha through interaction between the PDZ1 domain and ankyrin repeatsTyrosine phosphorylation of p62(Dok) induced by cell adhesion and insulin: possible role in cell migrationProtein tyrosine phosphatases expression during development of mouse superior colliculusA novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesionMolecular Basis of Gain-of-Function LEOPARD Syndrome-Associated SHP2 MutationsCrystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1Assembly and function of a cytosolic form of NADH-specific isocitrate dehydrogenase in yeast.The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsTyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factorsBrain-derived neurotrophic factor stimulates interactions of Shp2 with phosphatidylinositol 3-kinase and Grb2 in cultured cerebral cortical neuronsInhibition of EGFR-mediated phosphoinositide-3-OH kinase (PI3-K) signaling and glioblastoma phenotype by signal-regulatory proteins (SIRPs)Association of tyrosine phosphatase SHP-2 with F-actin at low cell densitiesInterleukin-3 induces the association of the inositol 5-phosphatase SHIP with SHP2Expression of protein-tyrosine phosphatases in the major insulin target tissuesShp2-mediated molecular signaling in control of embryonic stem cell self-renewal and differentiationThe COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signalingEpidermal growth factor induces coupling of protein-tyrosine phosphatase 1D to GRB2 via the COOH-terminal SH3 domain of GRB2Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signalingMolecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinasesFunctional importance of Shc tyrosine 317 on insulin signaling in Rat1 fibroblasts expressing insulin receptorsRole of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epitheliumCoupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responsesInsulin receptor substrate-1/SHP-2 interaction, a phenotype-dependent switching machinery of insulin-like growth factor-I signaling in vascular smooth muscle cellsSHP-2 mediates target-regulated axonal termination and NGF-dependent neurite growth in sympathetic neuronsShp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathwayDifferential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signalingThe role of the tyrosine kinase domain of the insulin-like growth factor-I receptor in intracellular signaling, cellular proliferation, and tumorigenesisCas mediates transcriptional activation of the serum response element by Src.
P2860
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P2860
Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Role of SH-PTP2, a protein-tyr ...... lin-stimulated Ras activation.
@ast
Role of SH-PTP2, a protein-tyr ...... lin-stimulated Ras activation.
@en
type
label
Role of SH-PTP2, a protein-tyr ...... lin-stimulated Ras activation.
@ast
Role of SH-PTP2, a protein-tyr ...... lin-stimulated Ras activation.
@en
prefLabel
Role of SH-PTP2, a protein-tyr ...... lin-stimulated Ras activation.
@ast
Role of SH-PTP2, a protein-tyr ...... lin-stimulated Ras activation.
@en
P2093
P2860
P356
P1476
Role of SH-PTP2, a protein-tyr ...... lin-stimulated Ras activation.
@en
P2093
P2860
P304
P356
10.1128/MCB.14.10.6674
P407
P577
1994-10-01T00:00:00Z