about
TREM2 in CNS homeostasis and neurodegenerative diseaseRhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activationThe myeloid receptor PILRβ mediates the balance of inflammatory responses through regulation of IL-27 productionMicrobial manipulation of receptor crosstalk in innate immunityLymphocytes and the Dap12 adaptor are key regulators of osteoclast activation associated with gonadal failure.Bone microenvironment specific roles of ITAM adapter signaling during bone remodeling induced by acute estrogen-deficiency.The SCHOOL of nature: I. Transmembrane signaling.The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia.TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway.Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.DAP12 is required for macrophage recruitment to the lung in response to cigarette smoke and chemotaxis toward CCL2DAP12 deficiency in liver allografts results in enhanced donor DC migration, augmented effector T cell responses and abrogation of transplant tolerance.Molecular dynamic simulation of the self-assembly of DAP12-NKG2C activating immunoreceptor complex.ITAM signaling in dendritic cells controls T helper cell priming by regulating MHC class II recycling.CD300b regulates the phagocytosis of apoptotic cells via phosphatidylserine recognition.The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses.The C-type lectin OCILRP2 costimulates EL4 T cell activation via the DAP12-Raf-MAP kinase pathway.DAP12 expression in lung macrophages mediates ischemia/reperfusion injury by promoting neutrophil extravasation.TREM-2 promotes macrophage survival and lung disease after respiratory viral infectionThe expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.Global expression profiling of peripheral Qa-1-restricted CD8αα+TCRαβ+ regulatory T cells reveals innate-like features: implications for immune-regulatory repertoireCalcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses.The Myeloid LSECtin Is a DAP12-Coupled Receptor That Is Crucial for Inflammatory Response Induced by Ebola Virus Glycoprotein.Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cellsEndoplasmic reticulum calcium depletion impacts chaperone secretion, innate immunity, and phagocytic uptake of cellsTriggering receptor expressed on myeloid cells and 5'adenosine monophosphate-activated protein kinase in the inflammatory response: a potential therapeutic target.Specific inactivation of two immunomodulatory SIGLEC genes during human evolution.BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties.Siglec-H protects from virus-triggered severe systemic autoimmunity.TLR-mediated signaling pathways circumvent the requirement for DAP12 in mast cells for the induction of inflammatory mediator release.PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon.The innate immune response to Salmonella enterica serovar Typhimurium by macrophages is dependent on TREM2-DAP12Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRgamma.Negative signaling by inhibitory receptors: the NK cell paradigm.DAP12 Inhibits Pulmonary Immune Responses to Cryptococcus neoformansTREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells.Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic ShockOsteoclasts - the innate immune cells of the bone.TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.Essential role of DAP12 signaling in macrophage programming into a fusion-competent state.
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description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Activating and inhibitory functions of DAP12.
@ast
Activating and inhibitory functions of DAP12.
@en
type
label
Activating and inhibitory functions of DAP12.
@ast
Activating and inhibitory functions of DAP12.
@en
prefLabel
Activating and inhibitory functions of DAP12.
@ast
Activating and inhibitory functions of DAP12.
@en
P2860
P356
P1476
Activating and inhibitory functions of DAP12.
@en
P2093
Isaiah R Turnbull
P2860
P304
P356
10.1038/NRI2014
P577
2007-01-15T00:00:00Z