TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.
about
TREM2 in CNS homeostasis and neurodegenerative diseaseMacrophages in intestinal homeostasis and inflammationMechanisms and potential therapeutic applications of microglial activation after brain injuryPathogenesis of infection in surgical patientsTriggering receptor expressed on myeloid cells receptor family modulators: a patent reviewStress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.Phagocytosis of apoptotic cells in homeostasisThe receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunityTREM2 and the neuroimmunology of Alzheimer's diseaseInsights into TREM2 biology by network analysis of human brain gene expression data.The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia.Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional rolesThe role of the microglia in acute CNS injury.The evolving biology of microglia in Alzheimer's disease.Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease.TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal CorticesThe expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.TREM-2 Receptor Expression Increases with 25(OH)D Vitamin Serum Levels in Patients with Pulmonary Sarcoidosis.Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental MelioidosisThe TREM2-DAP12 signaling pathway in Nasu-Hakola disease: a molecular genetics perspective.Molecular Characteristics of High-Dose Melphalan Associated Oral Mucositis in Patients with Multiple Myeloma: A Gene Expression Study on Human MucosaApolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).TREM2 regulates microglial cell activation in response to demyelination in vivo.The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.Chronic inflammation and cancer: emerging roles of triggering receptors expressed on myeloid cells.Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's diseaseOpposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation.TREM2 governs Kupffer cell activation and explains belr1 genetic resistance to malaria liver stage infectionPreparation, crystallization, and preliminary crystallographic analysis of wild-type and mutant human TREM-2 ectodomains linked to neurodegenerative and inflammatory diseasesMicroglial activation in stroke: therapeutic targets.Src-family and Syk kinases in activating and inhibitory pathways in innate immune cells: signaling cross talk.Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx.Information processing during phagocytosis.BACE1 influences debris clearance and axonal regeneration in injured peripheral nerve.Bacterial superinfection following lung inflammatory disorders.TREM2 in Alzheimer's disease.The innate immune system in Alzheimer's disease.Emerging roles for triggering receptor expressed on myeloid cells receptor family signaling in inflammatory diseases.Syk and Yea Shall Find.
P2860
Q26785919-23B318DF-7F53-49B6-9506-F6EE44FB26F8Q26851960-7040ACCE-CCE6-45FF-B200-287561FBF0E5Q26864358-64FEB8CD-A41A-48B4-A445-18C8D5976B83Q26995283-2550118D-B33A-4238-A3CB-ECD88F438146Q26999265-36B6FB92-C0B4-474F-AF10-DE529B6A6F04Q27311810-98AB248C-EA1F-4493-882F-C4303CD67EFFQ28081044-BEC3C919-5A3A-4D52-9BE2-6C1522EC43D7Q28260075-11E8E8B6-909A-49B9-9824-549668F68497Q28304401-A249F308-14B8-453A-AC67-F3E01945F4FBQ30655347-66F18CC1-D1A6-4C1E-99FA-D189C5386DCAQ33748966-EBF0EB48-519F-45BF-9639-08AAA2507A00Q33999537-926F726D-69DA-4255-AEF2-CB05F94BFB29Q34002086-A31322D3-E292-4C1E-8408-0A801978323AQ34266689-6E3B3C60-37A5-4276-852B-0DB8EA98E5D9Q35064995-23AAD26C-DBC0-44FE-BBEE-19EF73CB380BQ35515633-A8A5C2FC-9E8F-437D-8C7A-3A7AE3736D79Q35593790-DA1D98DB-983B-41DE-A86A-2F3FBAA9F43EQ35640941-F1F4B4EC-517B-41D7-B720-B9007A1AA68BQ35806789-13DB4283-CD7C-471D-A7F0-B1F2BED69CC4Q36037861-9DD512BB-F8E7-491A-A03D-00EE8145F2B0Q36161131-EB5484C5-54FE-4727-926F-0764B83DD9B9Q36239520-82C337AD-428E-46F2-956F-60C4384F4D29Q36283527-3A7F9352-B609-483F-8220-2D2DF86B7AC6Q36341689-242D50CB-EC4B-43B5-B50D-B10387434E68Q36385532-9530E55C-7583-4089-9B66-F745A0464BF2Q36793296-3A589EFB-BF8C-48DA-8941-1616E0371146Q36846582-BF16A9F9-BEC5-4D0D-B2D2-9DD5AB95B7CBQ36873059-EA7CE4D4-3651-4666-8363-5115874BB35CQ37352966-14702E51-865A-433A-8AD9-6951E97B10E9Q37693601-AF5746F2-D7EC-40F8-8BED-A14F86E4A7C9Q37794381-E6CEE497-8463-4D31-869C-FFF1B5FE7CA0Q37808572-35A7AE85-4E4E-4483-A16B-C669C49D6380Q38012092-BD5F788D-A32D-4D14-B280-A980213F926CQ38018843-75E141A6-826E-4757-B11A-46A1AF934F80Q38070883-1D43C043-8B84-46A9-9CA8-00C37DAFD0B1Q38078465-F6C92D00-1DE7-4AFF-8FA7-62429B93A02EQ38081367-4C091C02-43FE-4D4E-883D-E58252878618Q38162221-964A03D4-3FFC-4467-A273-5AA04F5241E1Q38170160-1E73C100-A895-42D9-A927-0ABDE8B5FC09Q38255421-8DFF7632-10ED-4EFF-A77F-40878248D8E2
P2860
TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
TREM-2 (triggering receptor ex ...... gocytic receptor for bacteria.
@en
TREM-2
@nl
type
label
TREM-2 (triggering receptor ex ...... gocytic receptor for bacteria.
@en
TREM-2
@nl
prefLabel
TREM-2 (triggering receptor ex ...... gocytic receptor for bacteria.
@en
TREM-2
@nl
P2093
P2860
P356
P1476
TREM-2 (triggering receptor ex ...... gocytic receptor for bacteria.
@en
P2093
Catherine S Branda
Clifford Lowell
Elsa-Noah N'Diaye
Jessica A Hamerman
Lisette Nevarez
Steven S Branda
William E Seaman
P2860
P304
P356
10.1083/JCB.200808080
P407
P577
2009-01-01T00:00:00Z