Tissue-specific transcription of the mouse alpha-fetoprotein gene promoter is dependent on HNF-1.
about
Regulation of alpha-fetoprotein expression by Nkx2.8HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitmentA novel nk-2-related transcription factor associated with human fetal liver and hepatocellular carcinomaA human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingersChromatin "prepattern" and histone modifiers in a fate choice for liver and pancreasMolecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gammaFunctional analysis of developmentally regulated chromatin-hypersensitive domains carrying the alpha 1-fetoprotein gene promoter and the albumin/alpha 1-fetoprotein intergenic enhancerraf regulates the postnatal repression of the mouse alpha-fetoprotein gene at the posttranscriptional levelMolecular cloning, functional expression, and chromosomal localization of mouse hepatocyte nuclear factor 1Mouse alpha-fetoprotein gene 5' regulatory elements are required for postnatal regulation by raf and RifVitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1alpha and 1betaFunctions of HNF1 family members in differentiation of the visceral endoderm cell lineageLFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epitheliaZinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liverATBF1, a multiple-homeodomain zinc finger protein, selectively down-regulates AT-rich elements of the human alpha-fetoprotein gene.AUF1-like protein binds specifically to DAS cis-acting element that regulates mouse alpha-fetoprotein gene expression.Alpha-fetoprotein related gene (ARG): a new member of the albumin gene family that is no longer functional in primatesFunctional characterization of a novel Ku70/80 pause site at the H19/Igf2 imprinting control regionTranscriptional control in hepatocytes of normal and c14CoS albino deletion mice.Definition and prediction of the full range of transcription factor binding sites--the hepatocyte nuclear factor 1 dimeric siteThe mouse alpha-albumin (afamin) promoter is differentially regulated by hepatocyte nuclear factor 1α and hepatocyte nuclear factor 1β.Expression from the tyrosine aminotransferase promoter (nt -350 to +1) is liver-specific and dependent on the binding of both liver-enriched and ubiquitous trans-acting factors.Homeostatic regulation of hepatocyte nuclear transcription factor 1 expression in cultured hepatoma cells.A promoter-linked coupling region required for stimulation of alpha-fetoprotein transcription by distant enhancers.Telomerase inhibition decreases alpha-fetoprotein expression and secretion by hepatocellular carcinoma cell lines: in vitro and in vivo study.Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region.Zhx2 and Zbtb20: novel regulators of postnatal alpha-fetoprotein repression and their potential role in gene reactivation during liver cancer.The binding site for the liver-specific transcription factor Tf-LF1 and the TATA box of the human transferrin gene promoter are the only elements necessary to direct liver-specific transcription in vitro.Independent regulation of HNF-1 alpha and HNF-1 beta by retinoic acid in F9 teratocarcinoma cells.alpha-Fetoprotein gene sequences mediating Afr2 regulation during liver regeneration.ZBTB20 is a sequence-specific transcriptional repressor of alpha-fetoprotein geneMolecular analysis of the distal enhancer of the mouse alpha-fetoprotein gene.Genetic analysis of a transcriptional activation pathway by using hepatoma cell variants.Negative and positive cis-acting elements control the expression of murine alpha 1-protease inhibitor genesRole of alpha-fetoprotein regulatory elements in transcriptional activation in transient heterokaryonsOverexpression of the multidrug resistance gene mdr3 in spontaneous and chemically induced mouse hepatocellular carcinomas.A position-dependent silencer plays a major role in repressing alpha-fetoprotein expression in human hepatoma.The genome of hepatitis B virus contains a second enhancer: cooperation of two elements within this enhancer is required for its function.A nuclease-hypersensitive element of the human c-myc promoter interacts with a transcription initiation factor.Promoter-specific transactivation of hepatitis B virus transcription by a glutamine- and proline-rich domain of hepatocyte nuclear factor 1.
P2860
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P2860
Tissue-specific transcription of the mouse alpha-fetoprotein gene promoter is dependent on HNF-1.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Tissue-specific transcription ...... romoter is dependent on HNF-1.
@ast
Tissue-specific transcription ...... romoter is dependent on HNF-1.
@en
type
label
Tissue-specific transcription ...... romoter is dependent on HNF-1.
@ast
Tissue-specific transcription ...... romoter is dependent on HNF-1.
@en
prefLabel
Tissue-specific transcription ...... romoter is dependent on HNF-1.
@ast
Tissue-specific transcription ...... romoter is dependent on HNF-1.
@en
P2093
P2860
P356
P1476
Tissue-specific transcription ...... romoter is dependent on HNF-1.
@en
P2093
M H Feuerman
R S Ingram
S M Tilghman
P2860
P304
P356
10.1128/MCB.9.10.4204
P407
P577
1989-10-01T00:00:00Z