Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity.
about
Human chemokine receptors CCR5, CCR3 and CCR2B share common polarity motif in the first extracellular loop with other human G-protein coupled receptors implications for HIV-1 coreceptor functionPivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxisGenomic organization and functional characterization of the chemokine receptor CXCR4, a major entry co-receptor for human immunodeficiency virus type 1Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway.The B-oligomer of pertussis toxin inhibits human immunodeficiency virus type 1 replication at multiple stages.Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation, and this is mediated through interaction of trichosanthin and chemokine receptorsApoptosis of uninfected cells induced by HIV envelope glycoproteinsHIV: cell binding and entryPotent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140Analysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodiesEffects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.A cyclic dodecapeptide-multiple-antigen peptide conjugate from the undecapeptidyl arch (from Arg(168) to Cys(178)) of extracellular loop 2 in CCR5 as a novel human immunodeficiency virus type 1 vaccineA novel cyclic peptide immunization strategy for preventing HIV-1/AIDS infection and progression.Fluorescence resonance energy transfer imaging reveals that chemokine-binding modulates heterodimers of CXCR4 and CCR5 receptors.The HIV envelope but not VSV glycoprotein is capable of mediating HIV latent infection of resting CD4 T cellsChemokine coreceptor signaling in HIV-1 infection and pathogenesis.Human immunodeficiency virus type 1 entry and chemokine receptors: a new therapeutic target.Identification of CXCR4 domains that support coreceptor and chemokine receptor functionsChemokine receptor trafficking and viral replication.Interference with the signaling capacity of CC chemokine receptor 5 can compromise its role as an HIV-1 entry coreceptor in primary T lymphocytes.An essential role of the cytoplasmic tail of CXCR4 in G-protein signaling and organogenesis.Genetic subtype-independent inhibition of human immunodeficiency virus type 1 replication by CC and CXC chemokines.Determinants of entry cofactor utilization and tropism in a dualtropic human immunodeficiency virus type 1 primary isolate.Influence of the CCR2-V64I polymorphism on human immunodeficiency virus type 1 coreceptor activity and on chemokine receptor function of CCR2b, CCR3, CCR5, and CXCR4.Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 delta32.Naturally occurring deletional mutation in the C-terminal cytoplasmic tail of CCR5 affects surface trafficking of CCR5.Molecular basis for cell tropism of CXCR4-dependent human immunodeficiency virus type 1 isolatesConstitutively active CCR5 chemokine receptors differ in mediating HIV envelope-dependent fusion.Chemokine receptors: emerging opportunities for new anti-HIV therapies.How does HIV-1 infect a susceptible human cell?: Current thinkingQuantitative analysis of the processes and signaling events involved in early HIV-1 infection of T cells.The tyrosine kinase inhibitor genistein blocks HIV-1 infection in primary human macrophages.Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency virusesThe trinity of the cortical actin in the initiation of HIV-1 infectiongp120 envelope glycoproteins of human immunodeficiency viruses competitively antagonize signaling by coreceptors CXCR4 and CCR5CCR5 mutations distinguish N-terminal modifications of RANTES (CCL5) with agonist versus antagonist activity.Host genetic determinants of HIV pathogenesis: an immunologic perspectiveHuman placental cytotrophoblasts attract monocytes and CD56(bright) natural killer cells via the actions of monocyte inflammatory protein 1alphaThe B-oligomer of pertussis toxin deactivates CC chemokine receptor 5 and blocks entry of M-tropic HIV-1 strains
P2860
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P2860
Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Molecular uncoupling of C-C ch ...... rom HIV-1 coreceptor activity.
@ast
Molecular uncoupling of C-C ch ...... rom HIV-1 coreceptor activity.
@en
type
label
Molecular uncoupling of C-C ch ...... rom HIV-1 coreceptor activity.
@ast
Molecular uncoupling of C-C ch ...... rom HIV-1 coreceptor activity.
@en
prefLabel
Molecular uncoupling of C-C ch ...... rom HIV-1 coreceptor activity.
@ast
Molecular uncoupling of C-C ch ...... rom HIV-1 coreceptor activity.
@en
P2093
P2860
P356
P1476
Molecular uncoupling of C-C ch ...... rom HIV-1 coreceptor activity.
@en
P2093
F S Monteclaro
M A Goldsmith
R E Atchison
P2860
P304
P356
10.1073/PNAS.94.10.5061
P407
P577
1997-05-01T00:00:00Z