Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice - Wikidata - wikimedia - TriplyDB

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice

http://www.wikidata.org/entity/Q36800423

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Acute overactive endocannabinoid signaling induces glucose intolerance, hepatic steatosis, and novel cannabinoid receptor 1 responsive genes The hepatic cannabinoid 1 receptor as a modulator of hepatic energy state and food intake Chemical probes of endocannabinoid metabolism The role of endocannabinoids system in fatty liver disease and therapeutic potentials Liver steatosis in hepatitis C patients Plasma and liver lipidomics response to an intervention of rimonabant in ApoE*3Leiden.CETP transgenic mice Endocannabinoid regulation of β-cell functions: implications for glycaemic control and diabetes Pharmacotherapeutic modulation of the endocannabinoid signalling system in psychiatric disorders: drug-discovery strategies Physical activity and the endocannabinoid system: an overview The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids Obesity: Current and potential pharmacotherapeutics and targets.Cannabinoids, eating behaviour, and energy homeostasis.Photoperiodic changes in endocannabinoid levels and energetic responses to altered signalling at CB1 receptors in Siberian hamsters.Endocannabinoid receptors gene expression in morbidly obese women with nonalcoholic fatty liver disease.Fatty Acid Binding Protein-1 (FABP1) and the Human FABP1 T94A Variant: Roles in the Endocannabinoid System and Dyslipidemias.Hepatitis C virus induces the cannabinoid receptor 1.Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implications.Role of cannabinoids in the development of fatty liver (steatosis)CB1 antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice Synthesis and structure-activity relationship studies of O-biphenyl-3-yl carbamates as peripherally restricted fatty acid amide hydrolase inhibitors.Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain.Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism Molecular pathways in non-alcoholic fatty liver disease.Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-gamma.The endocannabinoid system: potential for reducing cardiometabolic risk Cannabinoid receptor 1 gene polymorphisms and nonalcoholic Fatty liver disease in women with polycystic ovary syndrome and in healthy controls Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity.The endocannabinoid system links gut microbiota to adipogenesis Endocannabinoid signalling: has it got rhythm?CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake Nonhuman primates and other animal models in diabetes research.Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance.Beneficial metabolic effects of CB1R anti-sense oligonucleotide treatment in diet-induced obese AKR/J mice.Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects New insights on the role of the endocannabinoid system in the regulation of energy balance.Addiction research centres and the nurturing of creativity: the National Institute on Alcohol Abuse and Alcoholism.FABP1: A Novel Hepatic Endocannabinoid and Cannabinoid Binding Protein.

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Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice

http://www.wikidata.org/entity/Q36800423

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Hepatic CB1 receptor is requir ...... and leptin resistance in mice

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Hepatic CB1 receptor is requir ...... and leptin resistance in mice

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Hepatic CB1 receptor is requir ...... and leptin resistance in mice

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Hepatic CB1 receptor is requir ...... and leptin resistance in mice

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Hepatic CB1 receptor is requir ...... and leptin resistance in mice

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Hepatic CB1 receptor is requir ...... and leptin resistance in mice

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Journal of Clinical Investigation

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Hepatic CB1 receptor is requir ...... and leptin resistance in mice

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Beat Lutz

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Christoph Buettner

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George Kunos

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Grzegorz Godlewski

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Jie Liu

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Judith Harvey-White

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Liang Zhou

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Sándor Bátkai

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Won-il Jeong

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P2860

Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes

Apolipoprotein C-III: understanding an emerging cardiovascular risk factor

Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

Heavy marijuana users show increased serum apolipoprotein C-III levels: evidence from proteomic analyses

CB1 cannabinoid receptors and on-demand defense against excitotoxicity

Leptin-regulated endocannabinoids are involved in maintaining food intake

CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity

The emerging role of the endocannabinoid system in endocrine regulation and energy balance

Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice

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3160-3169

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10.1172/JCI34827

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9

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118

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Giovanni Marsicano

Douglas Osei-Hyiaman

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2008-09-01T00:00:00Z

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18677409

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2491458

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