Two regions of the adenovirus early region 1A proteins are required for transformation.
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The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycleMutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteinsMyc oncoproteins are phosphorylated by casein kinase IIDifferential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteinsOncolytic adenovirus research evolution: from cell-cycle checkpoints to immune checkpointsIdentification of a region of simian virus 40 large T antigen required for cell transformationp300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigenInduction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation.Adenovirus E1A243 disrupts the ATF/CREB-YY1 complex at the mouse c-fos promoter.Read-through activation of transcription in a cellular genomic contextComplex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.Expression of the pRb-binding regions of E1A enables efficient transformation of primary epithelial cells by v-src.Induction of transformation and p53-dependent apoptosis by adenovirus type 5 E4orf6/7 cDNA.Replication-selective adenoviruses as oncolytic agents.Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein.Oncolytic adenovirus: preclinical and clinical studies in patients with human malignant gliomas.Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins.Surprising dependency for retinoblastoma protein in ras-mediated tumorigenesisThe CtBP binding domain in the adenovirus E1A protein controls CR1-dependent transactivation.Downmodulation of E1A protein expression as a novel strategy to design cancer-selective adenoviruses.Function of a human cyclin gene as an oncogene.Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.E1A signaling to p53 involves the p19(ARF) tumor suppressor.Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A.Regulation of beta -catenin transformation by the p300 transcriptional coactivator.Efficient nuclear localization and immortalizing ability, two functions dependent on the adenovirus type 5 (Ad5) E1A second exon, are necessary for cotransformation with Ad5 E1B but not with T24rasSimian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107.Importance of the Ser-132 phosphorylation site in cell transformation and apoptosis induced by the adenovirus type 5 E1A protein.Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosisThe human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter.Distinct domains of adenovirus E1A interact with specific cellular factors to differentially modulate human immunodeficiency virus transcriptionAccumulation of p53 induced by the adenovirus E1A protein requires regions involved in the stimulation of DNA synthesis.Readthrough activation of early adenovirus E1b gene transcription.Structure-function analysis of the retinoblastoma tumor suppressor protein - is the whole a sum of its parts?Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma.Functional importance of complex formation between the retinoblastoma tumor suppressor family and adenovirus E1A proteins as determined by mutational analysis of E1A conserved region 2Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins.The adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2.Induction of gene expression by exon 2 of the major E1A proteins of adenovirus type 5.
P2860
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P2860
Two regions of the adenovirus early region 1A proteins are required for transformation.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Two regions of the adenovirus early region 1A proteins are required for transformation.
@en
type
label
Two regions of the adenovirus early region 1A proteins are required for transformation.
@en
prefLabel
Two regions of the adenovirus early region 1A proteins are required for transformation.
@en
P2093
P2860
P1433
P1476
Two regions of the adenovirus early region 1A proteins are required for transformation
@en
P2093
P2860
P304
P407
P577
1988-01-01T00:00:00Z