Accumulation of p53 induced by the adenovirus E1A protein requires regions involved in the stimulation of DNA synthesis.
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Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery.Regulation of the 26S proteasome by adenovirus E1AThe ORF3 protein of porcine circovirus type 2 interacts with porcine ubiquitin E3 ligase Pirh2 and facilitates p53 expression in viral infectionAdenovirus type 5 early region 1B 55K oncoprotein-dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cellsDegradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complexAnalysis of synthesis, stability, phosphorylation, and interacting polypeptides of the 34-kilodalton product of open reading frame 6 of the early region 4 protein of human adenovirus type 5The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis.Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A.p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication.Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complexInactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells.Transgenic expression in mouse lung reveals distinct biological roles for the adenovirus type 5 E1A 243- and 289-amino-acid proteinsVirotherapy targeting cyclin E overexpression in tumors with adenovirus-enhanced cancer-selective promoter.Eliminating established tumor in nu/nu nude mice by a tumor necrosis factor-alpha-related apoptosis-inducing ligand-armed oncolytic adenovirus.Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function.E1A signaling to p53 involves the p19(ARF) tumor suppressor.Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells.E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmkSelective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins.Oncolytic adenoviral vectors which employ the survivin promoter induce glioma oncolysis via a process of beclin-dependent autophagy.Suppression of adenovirus E1A-induced apoptosis by mutated p53 is overcome by coexpression with Id proteins.Role of E1B55K in E4orf6/E1B55K E3 ligase complexes formed by different human adenovirus serotypes.The replicative capacities of large E1B-null group A and group C adenoviruses are independent of host cell p53 statusThe E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity.Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes.p300 binding by E1A cosegregates with p53 induction but is dispensable for apoptosis.Normal human cell proteins that interact with the adenovirus type 5 E1B 55kDa protein.Recruitment of CBP/p300, TATA-binding protein, and S8 to distinct regions at the N terminus of adenovirus E1A.Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions.Modulation of p53 cellular function and cell death by African swine fever virus.p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing.
P2860
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P2860
Accumulation of p53 induced by the adenovirus E1A protein requires regions involved in the stimulation of DNA synthesis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Accumulation of p53 induced by ...... stimulation of DNA synthesis.
@ast
Accumulation of p53 induced by ...... stimulation of DNA synthesis.
@en
type
label
Accumulation of p53 induced by ...... stimulation of DNA synthesis.
@ast
Accumulation of p53 induced by ...... stimulation of DNA synthesis.
@en
prefLabel
Accumulation of p53 induced by ...... stimulation of DNA synthesis.
@ast
Accumulation of p53 induced by ...... stimulation of DNA synthesis.
@en
P2860
P1433
P1476
Accumulation of p53 induced by ...... e stimulation of DNA synthesis
@en
P2093
Branton PE
Teodoro JG
P2860
P304
P407
P577
1997-05-01T00:00:00Z