Epac/Rap and PKA are novel mechanisms of ANP-induced Rac-mediated pulmonary endothelial barrier protection. - Wikidata - wikimedia - TriplyDB

Epac/Rap and PKA are novel mechanisms of ANP-induced Rac-mediated pulmonary endothelial barrier protection.

Epac/Rap and PKA are novel mechanisms of ANP-induced Rac-mediated pulmonary endothelial barrier protection.

http://www.wikidata.org/entity/Q36840420

about

Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions Small G proteins in the cardiovascular system: physiological and pathological aspects Involvement of local lamellipodia in endothelial barrier function p21-Activated Kinase 2 Regulates Endothelial Development and Function through the Bmk1/Erk5 Pathway Signaling pathways that control rho kinase activity maintain the embryonic epicardial progenitor state.The cAMP-responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down-regulation of RhoA activity.Bacillus anthracis-derived edema toxin (ET) counter-regulates movement of neutrophils and macromolecules through the endothelial paracellular pathway.ANP attenuates inflammatory signaling and Rho pathway of lung endothelial permeability induced by LPS and TNFalpha.Lung endothelial barrier protection by iloprost in the 2-hit models of ventilator-induced lung injury (VILI) involves inhibition of Rho signaling.Adenosine protected against pulmonary edema through transporter- and receptor A2-mediated endothelial barrier enhancement Sphingosine-1-phosphate modulation of basal permeability and acute inflammatory responses in rat venular microvessels.Acute alcohol intoxication-induced microvascular leakage.Atrial natriuretic peptide attenuates LPS-induced lung vascular leak: role of PAK1.The future of EPAC-targeted therapies: agonism versus antagonism Role of microtubules in attenuation of PepG-induced vascular endothelial dysfunction by atrial natriuretic peptide.Epac and PKA: a tale of two intracellular cAMP receptors.Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo.Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier.Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction.Harvesting, identification and barrier function of human lung microvascular endothelial cells Atrial natriuretic peptide protects against Staphylococcus aureus-induced lung injury and endothelial barrier dysfunction Ras-related GTPases Rap1 and RhoA collectively induce the phagocytosis of serum-opsonized zymosan particles in macrophages Histamine activates p38 MAP kinase and alters local lamellipodia dynamics, reducing endothelial barrier integrity and eliciting central movement of actin fibers Attenuation by sphingosine-1-phosphate of rat microvessel acute permeability response to bradykinin is rapidly reversible.Endothelial actions of atrial and B-type natriuretic peptides Atrial natriuretic peptide attenuates agonist-induced pulmonary edema in mice with targeted disruption of the gene for natriuretic peptide receptor-A Association between adherens junctions and tight junctions via Rap1 promotes barrier protective effects of oxidized phospholipids.FTY720-induced human pulmonary endothelial barrier enhancement is mediated by c-Abl.The role of atrial natriuretic peptide to attenuate inflammation in a mouse skin wound and individually perfused rat mesenteric microvessels.Breaking the VE-cadherin bonds.Dendroaspis natriuretic peptide relaxes gastric antral circular smooth muscle of guinea-pig through the cGMP/cGMP-dependent protein kinase pathway.Increased microvascular permeability in mice lacking Epac1 (Rapgef3).EPAC proteins transduce diverse cellular actions of cAMP.Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics.Rap1 mediates protective effects of iloprost against ventilator-induced lung injury.Control of vascular permeability by atrial natriuretic peptide via a GEF-H1-dependent mechanism.The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.Regulation of smooth muscle contraction by small GTPases.Mitigation of chlorine lung injury by increasing cyclic AMP levels Emerging themes of cAMP regulation of the pulmonary endothelial barrier.

P2860

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P2860

Epac/Rap and PKA are novel mechanisms of ANP-induced Rac-mediated pulmonary endothelial barrier protection.

http://www.wikidata.org/entity/Q36840420

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Epac/Rap and PKA are novel mec ...... ndothelial barrier protection.

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type

label

Epac/Rap and PKA are novel mec ...... ndothelial barrier protection.

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Epac/Rap and PKA are novel mec ...... ndothelial barrier protection.

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Epac/Rap and PKA are novel mec ...... ndothelial barrier protection.

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Anna A Birukova

http://www.w3.org/2001/XMLSchema#string

Elena Alekseeva

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Gary M Bokoch

http://www.w3.org/2001/XMLSchema#string

Konstantin G Birukov

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Tatiana Zagranichnaya

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P2860

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

Molecular biology of the natriuretic peptides and their receptors

Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3

Regulatory and signaling properties of the Vav family

Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

Differential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretch

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Dbl family guanine nucleotide exchange factors

Inhibition of smooth muscle cell growth by nitric oxide and activation of cAMP-dependent protein kinase by cGMP

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10.1002/JCP.21354

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3

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215

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2008-06-01T00:00:00Z

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18064650

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3652875

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