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Identification of a region of simian virus 40 large T antigen required for cell transformationSimian virus 40 large T antigen: the puzzle, the pieces, and the emerging pictureGeometry of the simian virus 40 large tumor antigen-DNA complex as probed by protease digestionTopoisomerase I associates specifically with simian virus 40 large-T-antigen double hexamer-origin complexesRegulation of SV40 DNA replication by phosphorylation of T antigenNonspecific DNA binding activity of simian virus 40 large T antigen: evidence for the cooperation of two regions for full activity.Production of simian virus 40 large tumor antigen in bacteria: altered DNA-binding specificity and dna-replication activity of underphosphorylated large tumor antigen.Mechanisms of simian virus 40 T-antigen activation by phosphorylation of threonine 124Purification of the simian virus 40 (SV40) T antigen DNA-binding domain and characterization of its interactions with the SV40 origin.The N-terminal side of the origin-binding domain of simian virus 40 large T antigen is involved in A/T untwisting.Biochemical analysis of mutants with changes in the origin-binding domain of simian virus 40 tumor antigenThe 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitroStable T-p53 complexes are not required for replication of simian virus 40 in culture or for enhanced phosphorylation of T antigen and p53.Functional characterization of temperature-sensitive mutants of simian virus 40 large T antigenThe zinc finger region of simian virus 40 large T antigen is needed for hexamer assembly and origin meltingThe zinc finger region of simian virus 40 large T antigenIdentification of simian virus 40 T-antigen residues important for specific and nonspecific binding to DNA and for helicase activity.Identification of a 68-kilodalton nuclear ATP-binding phosphoprotein encoded by bovine papillomavirus type 1.Identification of functional regions in the yeast transcriptional activator ADR1.Thermally inactivated simian virus 40 tsA58 mutant T antigen cannot initiate viral DNA replication in vitroProperties of the DNA-binding domain of the simian virus 40 large T antigen.The human DNA-activated protein kinase phosphorylates simian virus 40 T antigen at amino- and carboxy-terminal sites.Four major sequence elements of simian virus 40 large T antigen coordinate its specific and nonspecific DNA binding.Mapping of helicase and helicase substrate-binding domains on simian virus 40 large T antigen.Large T-antigen mutants define multiple steps in the initiation of simian virus 40 DNA replicationTemperature-sensitive mutants identify crucial structural regions of simian virus 40 large T antigenPhosphorylation downregulates the DNA-binding activity of simian virus 40 T antigen.Studies on the origin-specific DNA-binding domain of simian virus 40 large T antigenRemoval of serine phosphates from simian virus 40 large T antigen increases its ability to stimulate DNA replication in vitro but has no effect on ATPase and DNA bindingNonspecific double-stranded DNA binding activity of simian virus 40 large T antigen is involved in melting and unwinding of the origin.Expression and interactions of human adenovirus oncoproteins.Biochemical characterization of phosphorylation site mutants of simian virus 40 large T antigen: evidence for interaction between amino- and carboxy-terminal domains.Mutations in the phosphorylation sites of simian virus 40 (SV40) T antigen alter its origin DNA-binding specificity for sites I or II and affect SV40 DNA replication activity.Recognition mechanisms in the synthesis of animal virus DNA.The DNA-binding domain of simian virus 40 tumor antigen has multiple functions.Effects of in vitro dephosphorylation on DNA-binding and DNA helicase activities of simian virus 40 large tumor antigen.Expression of simian virus 40 T antigen in Escherichia coli: localization of T-antigen origin DNA-binding domain to within 129 amino acids.Monoclonal antibodies as probes for a function of large T antigen during the elongation process of simian virus 40 DNA replication.Simian virus 40 large T antigen can specifically unwind the central palindrome at the origin of DNA replication.
P2860
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P2860
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
DNA-binding region of the simian virus 40 tumor antigen
@en
type
label
DNA-binding region of the simian virus 40 tumor antigen
@en
prefLabel
DNA-binding region of the simian virus 40 tumor antigen
@en
P2860
P1433
P1476
DNA-binding region of the simian virus 40 tumor antigen
@en
P2093
D T Simmons
P2860
P304
P407
P577
1986-03-01T00:00:00Z