Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1
about
Role of Nrf2 in oxidative stress and toxicityDJ-1 induces thioredoxin 1 expression through the Nrf2 pathwayPathogenic triad in COPD: oxidative stress, protease-antiprotease imbalance, and inflammationN-acetylcysteine in COPD: why, how, and when?Pathobiology of tobacco smoking and neurovascular disorders: untied strings and alternative productsEndogenous Generation and Signaling Actions of Omega-3 Fatty Acid Electrophilic DerivativesSirtuin 1 and aging theory for chronic obstructive pulmonary diseaseOxidative stress and free radicals in COPD--implications and relevance for treatmentOxidative stress and respiratory system: pharmacological and clinical reappraisal of N-acetylcysteineEmerging functional cross-talk between the Keap1-Nrf2 system and mitochondriaInterrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatmentsCross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for CancerCellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disordersStress-activated cap'n'collar transcription factors in aging and human diseaseNrf2 expression is increased in peripheral blood mononuclear cells derived from mild-moderate ex-smoker COPD patients with persistent oxidative stressNeu-164 and Neu-107, two novel antioxidant and anti-myeloperoxidase compounds, inhibit acute cigarette smoke-induced lung inflammationNrf2 regulates chronic lung inflammation and B-cell responses to nontypeable Haemophilus influenzaeCigarette smoking blocks the protective expression of Nrf2/ARE pathway in peripheral mononuclear cells of young heavy smokers favouring inflammationNrf2 is required for normal postnatal bone acquisition in miceMolecular basis for vulnerability to mitochondrial and oxidative stress in a neuroendocrine CRI-G1 cell lineDJ-1-dependent regulation of oxidative stress in the retinal pigment epithelium (RPE)Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in ratsMechanistic Nanotherapeutic Approach Based on siRNA-Mediated DJ-1 Protein Suppression for Platinum-Resistant Ovarian CancerHeightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity.SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanismBromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression.Induction of heme oxygenase-1, biliverdin reductase and H-ferritin in lung macrophage in smokers with primary spontaneous pneumothorax: role of HIF-1alphaNrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs.DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.NFE2L2 polymorphisms, mortality, and metabolism in the general population.Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation.Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout miceLarge-scale proteomics differentiates cholesteatoma from surrounding tissues and identifies novel proteins related to the pathogenesis.Human alveolar epithelial cell injury induced by cigarette smokeExtracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM.Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis.Decreased DJ-1 leads to impaired Nrf2-regulated antioxidant defense and increased UV-A-induced apoptosis in corneal endothelial cells.Suppressed expression of T-box transcription factors is involved in senescence in chronic obstructive pulmonary disease.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction.
P2860
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P2860
Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Decline in NRF2-regulated anti ...... f its positive regulator, DJ-1
@en
type
label
Decline in NRF2-regulated anti ...... f its positive regulator, DJ-1
@en
prefLabel
Decline in NRF2-regulated anti ...... f its positive regulator, DJ-1
@en
P2093
P2860
P1476
Decline in NRF2-regulated anti ...... f its positive regulator, DJ-1
@en
P2093
Ana Navas-Acien
Andrew Sandford
Anju Singh
Deepti Malhotra
James Hogg
Linan Chen
Mark Elliott
Peter Pare
Rajesh Thimmulappa
Rubin M Tuder
P2860
P304
P356
10.1164/RCCM.200803-380OC
P407
P577
2008-06-12T00:00:00Z