Processing of p60v-src to its myristylated membrane-bound form
about
Characterization of cDNA clones for the human c-yes geneA noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fpsChemical characterization of p17gag from human immunodeficiency virus as an N-terminally myristoylated proteinSite-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src.Tyrosine phosphorylation of three cellular proteins correlates with transformation of rat 1 cells by pp60src.Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteinsAssociation of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation.Sequences of the bovine and yeast ADP-ribosylation factor and comparison to other GTP-binding proteins.c-src gene product in developing rat brain is enriched in nerve growth cone membranesAltered membrane association of p60v-src and a murine 63-kDa N-myristoyl protein after incorporation of an oxygen-substituted analog of myristic acidThe src protein contains multiple domains for specific attachment to membranes.NH2-terminal sequences of two src proteins that cause aberrant transformationCharacterization of avian and viral p60src proteins expressed in yeastIdentification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling.Activation of the transforming potential of p60c-src by a single amino acid changeMyristylation site in Pr65gag is essential for virus particle formation by Moloney murine leukemia virusSpecific association of the proto-oncogene product pp60c-src with an intracellular organelle, the PC12 synaptic vesicleLysine residues form an integral component of a novel NH2-terminal membrane targeting motif for myristylated pp60v-src.Identification of human immunodeficiency virus type 1 Gag protein domains essential to membrane binding and particle assembly.Enhancement of transforming potential of human insulinlike growth factor 1 receptor by N-terminal truncation and fusion to avian sarcoma virus UR2 gag sequence.The ADP/ATP carrier is the 32-kilodalton receptor for an NH2-terminally myristylated src peptide but not for pp60src polypeptideA myristylated form of the sea oncoprotein can transform chicken embryo fibroblastsp59fyn tyrosine kinase associates with multiple T-cell receptor subunits through its unique amino-terminal domain.A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent mannerThe first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinant.Suppression of Rous sarcoma virus-induced tumor formation by preinfection with viruses encoding src protein with novel N termini.DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes.The six amino-terminal amino acids of p60src are sufficient to cause myristylation of p21v-ras.The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activityGenetic analysis of p60v-src domains involved in the induction of different cell transformation parameters.Biochemical properties of p60v-src mutants that induce different cell transformation parameters.Analysis of p60v-src mutants carrying lesions involved in temperature sensitivityMyristylation is required for intracellular transport but not for assembly of D-type retrovirus capsids.The membrane-binding domain and myristylation of p60v-src are not essential for stimulation of cell proliferation.Creation of a chimeric oncogene: analysis of the biochemical and biological properties of v-erbB/src fusion polypeptideN-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src geneRous sarcoma virus mutant dlPA105 induces different transformed phenotypes in quail embryonic fibroblasts and neuroretina cells.Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymesThe caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.
P2860
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P2860
Processing of p60v-src to its myristylated membrane-bound form
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
Processing of p60v-src to its myristylated membrane-bound form
@en
type
label
Processing of p60v-src to its myristylated membrane-bound form
@en
prefLabel
Processing of p60v-src to its myristylated membrane-bound form
@en
P2093
P2860
P356
P1476
Processing of p60v-src to its myristylated membrane-bound form
@en
P2093
P2860
P304
P356
10.1128/MCB.5.10.2781
P407
P577
1985-10-01T00:00:00Z