The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency.
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A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core DomainLEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIVComputational and synthetic approaches for developing Lavendustin B derivatives as allosteric inhibitors of HIV-1 integraseStructure and Dynamics of the Liver Receptor Homolog 1-PGC1α Complex.Allosteric HIV-1 integrase inhibitors promote aberrant protein multimerization by directly mediating inter-subunit interactions: Structural and thermodynamic modeling studies.Cellular and molecular mechanisms of HIV-1 integration targeting.Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration.Synthesis and Evaluation of Aryl Quinolines as HIV-1 Integrase Multimerization Inhibitors
P2860
Q27728086-43200C56-B152-43BA-8241-140F631CA3B8Q37035177-09B4A052-3278-4DCB-94A9-8A8D7AEBE5F5Q37616219-27977518-7A50-4FEF-8187-41C17F1A3033Q38432226-C4E11832-0766-4E19-A69B-288B1B681A91Q40519415-83B89206-E793-43E1-8096-4CB1FFB8A612Q50126703-6D8B66FC-371B-462A-9C60-2458EB7013AEQ52673279-2D4B9787-18B1-43B8-9247-62805A807C07Q57822203-309B7476-920D-4CD9-B8A3-8390EA89B8FE
P2860
The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
The Competitive Interplay betw ...... ely Affects Inhibitor Potency.
@en
type
label
The Competitive Interplay betw ...... ely Affects Inhibitor Potency.
@en
prefLabel
The Competitive Interplay betw ...... ely Affects Inhibitor Potency.
@en
P2093
P2860
P1433
P1476
The Competitive Interplay betw ...... ely Affects Inhibitor Potency.
@en
P2093
Alan N Engelman
Alison Slaughter
Amit Sharma
Ashley Hoyte
Erik Serrao
Frederic D Bushman
Jacques J Kessl
James R Fuchs
Matthew R Plumb
P2860
P304
P356
10.1021/ACSCHEMBIO.6B00167
P577
2016-02-24T00:00:00Z