Genetic ablation of M3 muscarinic receptors attenuates murine colon epithelial cell proliferation and neoplasia.
about
Differential expression of M3 muscarinic receptors in progressive colon neoplasia and metastasisDivergent effects of muscarinic receptor subtype gene ablation on murine colon tumorigenesis reveals association of M3R and zinc finger protein 277 expression in colon neoplasia.Bedside to bench: role of muscarinic receptor activation in ultrarapid growth of colorectal cancer in a patient with pheochromocytoma.Scopolamine treatment and muscarinic receptor subtype-3 gene ablation augment azoxymethane-induced murine liver injury.Src-mediated cross-talk between farnesoid X and epidermal growth factor receptors inhibits human intestinal cell proliferation and tumorigenesis.Regulation of M₃ muscarinic receptor expression and function by transmembrane protein 147.Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesisMuscarinic receptor agonists stimulate human colon cancer cell migration and invasion.Structural basis of M3 muscarinic receptor dimer/oligomer formationMuscarinic receptor subtype-3 gene ablation and scopolamine butylbromide treatment attenuate small intestinal neoplasia in Apcmin/+ mice.Denervation suppresses gastric tumorigenesis.Muscarinic receptor agonists stimulate matrix metalloproteinase 1-dependent invasion of human colon cancer cellsSlc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids.Muscarinic receptor agonists and antagonists: effects on cancerAcetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation.Muscarinic receptors and ligands in cancer.MACC1 mediates acetylcholine-induced invasion and migration by human gastric cancer cells.Cholinergic Targets in Lung CancerMuscarinic receptor signaling in colon cancer.Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cellsHypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasisNovel insights into M3 muscarinic acetylcholine receptor physiology and structure.Muscarinic acetylcholine receptors: novel opportunities for drug development.Effect of bronchodilators on bronchial gland cell proliferation after inhalation and burn injury in sheep.Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells.Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD).Acetylcholine-related proteins in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia.Activation of M3 muscarinic receptor by acetylcholine promotes non-small cell lung cancer cell proliferation and invasion via EGFR/PI3K/AKT pathway.EGFR and PKC are involved in the activation of ERK1/2 and p90 RSK and the subsequent proliferation of SNU-407 colon cancer cells by muscarinic acetylcholine receptors.High expression of M3 muscarinic acetylcholine receptor is a novel biomarker of poor prognostic in patients with non-small cell lung cancer.Cholinergic Machinery as Relevant Target in Acute Lymphoblastic T LeukemiaThe ERK1/2 and mTORC1 Signaling Pathways Are Involved in the Muscarinic Acetylcholine Receptor-Mediated Proliferation of SNU-407 Colon Cancer Cells.Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells.Extrinsic intestinal denervation modulates tumor development in the small intestine of Apc(Min/+) mice.Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling.Muscarinic receptor M3 mediates cell proliferation induced by acetylcholine and contributes to apoptosis in gastric cancer.High capacity in G protein-coupled receptor signaling.Intestinal Epithelial Wnt Signaling Mediates Acetylcholine-Triggered Host Defense against Infection.Diminished gallbladder filling, increased fecal bile acids, and promotion of colon epithelial cell proliferation and neoplasia in fibroblast growth factor 15-deficient mice.Immunoglobulin g from breast cancer patients regulates MCF-7 cells migration and MMP-9 activity by stimulating muscarinic acetylcholine receptors
P2860
Q33591457-67D4B14F-779B-4735-A5B8-8D6724E0899DQ33612122-F0DCD53E-7B0E-4D5A-ACE8-DA2800D9713EQ33828152-82EA03C1-D7B7-4A48-8EDF-298716AE652EQ33890928-27E4261B-42EC-4900-9151-EA3C2F894EF1Q34465146-F75D2CB3-0BE1-4873-A6DE-F9ECBAE1155AQ34552040-3AFAF6CD-502A-4A95-9DB8-4DE4E06105CFQ34687201-E575FD13-D845-48BC-9E74-B11F8423CE13Q34979987-0167F7D0-F25A-46BC-9F80-48F8780153A5Q35150277-E509D612-85BE-4122-A0F8-AB15CC18FF2AQ35190800-2833C3CC-6149-48C6-9E5D-A094DB910516Q35219277-9FF0804F-669B-44B9-A3EE-3B18A323EE4BQ35566735-075FFC05-0B1F-47C1-96FA-B095C0980E93Q36181327-ACBE2F8E-99E8-4855-B7F0-AFFC8986FB3FQ36706667-D2B21A52-C96C-4B7B-9EB2-D3472A34A2C0Q36877273-5222657C-9A19-45A4-BF50-E8CE5C0EDCF3Q37100030-2A1309C6-38BF-47C8-94B4-FDFD977065CBQ37109689-DA59AB24-C043-41F8-9B79-A5AB579B0644Q37127226-E52FC541-1378-4A2D-8FA8-926D847A84CAQ37129839-C095EC7A-4B85-4322-8878-7163A9303A66Q37162439-41E69217-F391-45BF-9298-D20BE8432789Q37446488-F1E5EF96-7C01-4A69-8806-7DDE262B58F6Q37666222-6C59267C-9AF4-4BDE-9D81-DCA11D23CA91Q38218059-125FBCFA-7273-4CA8-8AD4-BBBFEDCEF87BQ38400351-C290F2F2-759F-4567-8484-493C4DB9B2A9Q38724705-970DC29F-8E85-4FB1-AF6C-72F663EDB2B8Q38760403-BBBCB661-5EC0-45ED-869D-3B82184A81A3Q38763984-13AC2917-922B-44F2-9E6F-F7DB4AEF8186Q38876262-A15A87EE-C57E-49AD-BA87-6752455F7102Q39302081-FCCF87DA-67A3-41A0-A93D-597BA98F4F34Q39387875-0B42FE7A-E7D2-4459-9B05-ACB345C6A578Q39388169-94678BEE-D437-4954-AC71-3A14873AD335Q39775886-0374E593-7AFC-402F-BF8F-D7EA3C028F22Q39823738-BDD5CFDB-B6DB-47D3-8944-AC37EDB48133Q40943251-6E9B706B-A911-4050-A96B-65BD331C5185Q51252178-F5C28AE1-7923-49A4-B20B-3CF7CC22B72CQ53359349-9356DE5C-D988-44E2-9A03-63D3AB489C12Q53701656-CF18C88A-AD80-48B9-BFE0-AF20969E3636Q54210129-98DA0B17-E7C2-4E77-B132-6121BA075F55Q55003380-DF24B44D-6C82-42C3-B061-5F08F240F659Q56773128-10321434-EB82-4613-A246-D06C59A9FA7E
P2860
Genetic ablation of M3 muscarinic receptors attenuates murine colon epithelial cell proliferation and neoplasia.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Genetic ablation of M3 muscari ...... l proliferation and neoplasia.
@en
type
label
Genetic ablation of M3 muscari ...... l proliferation and neoplasia.
@en
prefLabel
Genetic ablation of M3 muscari ...... l proliferation and neoplasia.
@en
P2093
P2860
P1433
P1476
Genetic ablation of M3 muscari ...... l proliferation and neoplasia.
@en
P2093
Cinthia Drachenberg
Guofeng Xie
Jasleen Shant
Jean-Pierre Raufman
Jürgen Wess
Kunrong Cheng
Nirish Shah
Roxana Samimi
Sandeep Khurana
P2860
P304
P356
10.1158/0008-5472.CAN-07-6810
P407
P577
2008-05-01T00:00:00Z